PDB entry 6lw1

View 6lw1 on RCSB PDB site
Description: cryo-em structure of tlr7/cpd-7 (dsr-139970) complex in open form
Deposited on 2020-02-06, released 2020-11-11
The last revision was dated 2020-11-11, with a file datestamp of 2020-11-06.
Experiment type: EM
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 7
    Species: Macaca mulatta [TaxId:9544]
    Gene: TLR7
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3Y653 (4-End)
      • engineered mutation (144)
      • engineered mutation (366)
      • engineered mutation (776)
  • Chain 'B':
    Compound: Toll-like receptor 7
    Species: Macaca mulatta [TaxId:9544]
    Gene: TLR7
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3Y653 (4-End)
      • engineered mutation (144)
      • engineered mutation (366)
      • engineered mutation (776)
  • Heterogens: EX3

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6lw1A (A:)
rspwarwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdisp
asfhrlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqllei
pqglppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdafln
ltklkvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncpr
cynapfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldls
qnflakeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvf
kelksfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispsgdslvp
rgssnartsvesyepqvleqlyyfrydkyarscrfknkeasftsvqescykygqtldlsk
nsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnnrldllhstaf
eelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissstsrtmeseslr
tlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdgmppnlknlsl
aknglksfiweklrylknletldlshnqlttvperlsncsrslknlilknnqirsltkyf
lqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdavwfvwwvqhte
vtipylatdvtcvgpgahkgqsvisldlytceldltneflvpr

    Sequence, based on observed residues (ATOM records):
    >6lw1A (A:)
arwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdispasfh
rlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqlleipqgl
ppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdaflnltkl
kvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncprcyna
pfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldlsqnfl
akeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvfkelk
sfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispydkyarscscy
kygqtldlsknsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnn
rldllhstafeelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissst
srtmeseslrtlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdg
mppnlknlslaknglksfiweklrylknletldlshnqlttvperlsncsrslknlilkn
nqirsltkyflqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdav
wfvwwvqhtevtipylatdvtcvgpgahkgqsvisldlytcel

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6lw1B (B:)
rspwarwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdisp
asfhrlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqllei
pqglppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdafln
ltklkvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncpr
cynapfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldls
qnflakeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvf
kelksfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispsgdslvp
rgssnartsvesyepqvleqlyyfrydkyarscrfknkeasftsvqescykygqtldlsk
nsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnnrldllhstaf
eelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissstsrtmeseslr
tlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdgmppnlknlsl
aknglksfiweklrylknletldlshnqlttvperlsncsrslknlilknnqirsltkyf
lqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdavwfvwwvqhte
vtipylatdvtcvgpgahkgqsvisldlytceldltneflvpr

    Sequence, based on observed residues (ATOM records):
    >6lw1B (B:)
arwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdispasfh
rlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqlleipqgl
ppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdaflnltkl
kvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncprcyna
pfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldlsqnfl
akeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvfkelk
sfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispydkyarscscy
kygqtldlsknsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnn
rldllhstafeelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissst
srtmeseslrtlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdg
mppnlknlslaknglksfiweklrylknletldlshnqlttvperlsncsrslknlilkn
nqirsltkyflqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdav
wfvwwvqhtevtipylatdvtcvgpgahkgqsvisldlytcel