PDB entry 6lw0

View 6lw0 on RCSB PDB site
Description: crystal structure of tlr7/cpd-6 (dsr-139293) complex
Deposited on 2020-02-06, released 2020-11-11
The last revision was dated 2020-11-11, with a file datestamp of 2020-11-06.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 7
    Species: Macaca mulatta [TaxId:9544]
    Gene: TLR7
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3Y653 (4-End)
      • engineered mutation (144)
      • engineered mutation (366)
      • engineered mutation (776)
  • Chain 'B':
    Compound: Toll-like receptor 7
    Species: Macaca mulatta [TaxId:9544]
    Gene: TLR7
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3Y653 (4-End)
      • engineered mutation (144)
      • engineered mutation (366)
      • engineered mutation (776)
  • Heterogens: EX0, NAG, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6lw0A (A:)
rspwarwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdisp
asfhrlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqllei
pqglppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdafln
ltklkvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncpr
cynapfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldls
qnflakeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvf
kelksfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispsgdslvp
rgssnartsvesyepqvleqlyyfrydkyarscrfknkeasftsvqescykygqtldlsk
nsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnnrldllhstaf
eelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissstsrtmeseslr
tlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdgmppnlknlsl
aknglksfiweklrylknletldlshnqlttvperlsncsrslknlilknnqirsltkyf
lqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdavwfvwwvqhte
vtipylatdvtcvgpgahkgqsvisldlytceldltneflvpr

    Sequence, based on observed residues (ATOM records):
    >6lw0A (A:)
arwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdispasfh
rlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqlleipqgl
ppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdaflnltkl
kvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncprcyna
pfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldlsqnfl
akeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvfkelk
sfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispvleqlyyfryd
kyarscscykygqtldlsknsiffikssdfqhlsflkclnlsgnlisqtlngsefqplae
lryldfsnnrldllhstafeelrklevldissnshyfqsegithmlnftknlkvlqklmm
ndndissstsrtmeseslrtlefrgnhldvlwrdgdnrylqlfknllkleeldisknsls
flpsgvfdgmppnlknlslaknglksfiweklrylknletldlshnqlttvperlsncsr
slknlilknnqirsltkyflqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhn
rflctcdavwfvwwvqhtevtipylatdvtcvgpgahkgqsvisldlytcel

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6lw0B (B:)
rspwarwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdisp
asfhrlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqllei
pqglppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdafln
ltklkvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncpr
cynapfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldls
qnflakeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvf
kelksfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispsgdslvp
rgssnartsvesyepqvleqlyyfrydkyarscrfknkeasftsvqescykygqtldlsk
nsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnnrldllhstaf
eelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissstsrtmeseslr
tlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdgmppnlknlsl
aknglksfiweklrylknletldlshnqlttvperlsncsrslknlilknnqirsltkyf
lqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdavwfvwwvqhte
vtipylatdvtcvgpgahkgqsvisldlytceldltneflvpr

    Sequence, based on observed residues (ATOM records):
    >6lw0B (B:)
arwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdispasfh
rlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqlleipqgl
ppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdaflnltkl
kvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncprcyna
pfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldlsqnfl
akeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvfkelk
sfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispvleqlyyfryd
kyarscscykygqtldlsknsiffikssdfqhlsflkclnlsgnlisqtlngsefqplae
lryldfsnnrldllhstafeelrklevldissnshyfqsegithmlnftknlkvlqklmm
ndndissstsrtmeseslrtlefrgnhldvlwrdgdnrylqlfknllkleeldisknsls
flpsgvfdgmppnlknlslaknglksfiweklrylknletldlshnqlttvperlsncsr
slknlilknnqirsltkyflqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhn
rflctcdavwfvwwvqhtevtipylatdvtcvgpgahkgqsvisldlytcel