PDB entry 6lto

View 6lto on RCSB PDB site
Description: cryo-em structure of full length human pannexin1
Deposited on 2020-01-23, released 2020-05-13
The last revision was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: EM
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pannexin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PANX1, MRS1, UNQ2529/PRO6028
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Pannexin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PANX1, MRS1, UNQ2529/PRO6028
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Pannexin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PANX1, MRS1, UNQ2529/PRO6028
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Pannexin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PANX1, MRS1, UNQ2529/PRO6028
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Pannexin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PANX1, MRS1, UNQ2529/PRO6028
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Pannexin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PANX1, MRS1, UNQ2529/PRO6028
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Pannexin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PANX1, MRS1, UNQ2529/PRO6028
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ltoA (A:)
maiaqlateyvfsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisi
gtqiscfspssfswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaill
ylpplfwrfaaaphicsdlkfimeeldkvynraikaaksardldmrdgacsvpgvtenlg
qslwevseshfkypiveqylktkknsnnliikyiscrlltliiillaciylgyyfslssl
sdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvllapvvvytlfvpfr
qktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksykclkvlenikssgqg
idpmllltnlgmikmdvvdgktpmsaemreeqgnqtaelqgmnidsetkanngeknarqr
lldssclewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ltoA (A:)
fsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisigtqiscfspss
fswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaillylpplfwrfaa
aphicsdlkfimeeldkvynraikaakpiveqylktkknsnnliikyiscrlltliiill
aciylgyyfslsslsdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvl
lapvvvytlfvpfrqktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksyk
clkvleni

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ltoB (B:)
maiaqlateyvfsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisi
gtqiscfspssfswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaill
ylpplfwrfaaaphicsdlkfimeeldkvynraikaaksardldmrdgacsvpgvtenlg
qslwevseshfkypiveqylktkknsnnliikyiscrlltliiillaciylgyyfslssl
sdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvllapvvvytlfvpfr
qktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksykclkvlenikssgqg
idpmllltnlgmikmdvvdgktpmsaemreeqgnqtaelqgmnidsetkanngeknarqr
lldssclewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ltoB (B:)
fsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisigtqiscfspss
fswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaillylpplfwrfaa
aphicsdlkfimeeldkvynraikaakpiveqylktkknsnnliikyiscrlltliiill
aciylgyyfslsslsdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvl
lapvvvytlfvpfrqktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksyk
clkvleni

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ltoC (C:)
maiaqlateyvfsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisi
gtqiscfspssfswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaill
ylpplfwrfaaaphicsdlkfimeeldkvynraikaaksardldmrdgacsvpgvtenlg
qslwevseshfkypiveqylktkknsnnliikyiscrlltliiillaciylgyyfslssl
sdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvllapvvvytlfvpfr
qktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksykclkvlenikssgqg
idpmllltnlgmikmdvvdgktpmsaemreeqgnqtaelqgmnidsetkanngeknarqr
lldssclewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ltoC (C:)
fsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisigtqiscfspss
fswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaillylpplfwrfaa
aphicsdlkfimeeldkvynraikaakpiveqylktkknsnnliikyiscrlltliiill
aciylgyyfslsslsdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvl
lapvvvytlfvpfrqktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksyk
clkvleni

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ltoD (D:)
maiaqlateyvfsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisi
gtqiscfspssfswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaill
ylpplfwrfaaaphicsdlkfimeeldkvynraikaaksardldmrdgacsvpgvtenlg
qslwevseshfkypiveqylktkknsnnliikyiscrlltliiillaciylgyyfslssl
sdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvllapvvvytlfvpfr
qktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksykclkvlenikssgqg
idpmllltnlgmikmdvvdgktpmsaemreeqgnqtaelqgmnidsetkanngeknarqr
lldssclewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ltoD (D:)
fsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisigtqiscfspss
fswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaillylpplfwrfaa
aphicsdlkfimeeldkvynraikaakpiveqylktkknsnnliikyiscrlltliiill
aciylgyyfslsslsdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvl
lapvvvytlfvpfrqktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksyk
clkvleni

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6ltoE (E:)
maiaqlateyvfsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisi
gtqiscfspssfswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaill
ylpplfwrfaaaphicsdlkfimeeldkvynraikaaksardldmrdgacsvpgvtenlg
qslwevseshfkypiveqylktkknsnnliikyiscrlltliiillaciylgyyfslssl
sdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvllapvvvytlfvpfr
qktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksykclkvlenikssgqg
idpmllltnlgmikmdvvdgktpmsaemreeqgnqtaelqgmnidsetkanngeknarqr
lldssclewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ltoE (E:)
fsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisigtqiscfspss
fswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaillylpplfwrfaa
aphicsdlkfimeeldkvynraikaakpiveqylktkknsnnliikyiscrlltliiill
aciylgyyfslsslsdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvl
lapvvvytlfvpfrqktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksyk
clkvleni

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6ltoF (F:)
maiaqlateyvfsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisi
gtqiscfspssfswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaill
ylpplfwrfaaaphicsdlkfimeeldkvynraikaaksardldmrdgacsvpgvtenlg
qslwevseshfkypiveqylktkknsnnliikyiscrlltliiillaciylgyyfslssl
sdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvllapvvvytlfvpfr
qktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksykclkvlenikssgqg
idpmllltnlgmikmdvvdgktpmsaemreeqgnqtaelqgmnidsetkanngeknarqr
lldssclewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ltoF (F:)
fsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisigtqiscfspss
fswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaillylpplfwrfaa
aphicsdlkfimeeldkvynraikaakpiveqylktkknsnnliikyiscrlltliiill
aciylgyyfslsslsdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvl
lapvvvytlfvpfrqktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksyk
clkvleni

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6ltoG (G:)
maiaqlateyvfsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisi
gtqiscfspssfswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaill
ylpplfwrfaaaphicsdlkfimeeldkvynraikaaksardldmrdgacsvpgvtenlg
qslwevseshfkypiveqylktkknsnnliikyiscrlltliiillaciylgyyfslssl
sdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvllapvvvytlfvpfr
qktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksykclkvlenikssgqg
idpmllltnlgmikmdvvdgktpmsaemreeqgnqtaelqgmnidsetkanngeknarqr
lldssclewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ltoG (G:)
fsdfllkeptepkfkglrlelavdkmvtciavglplllislafaqeisigtqiscfspss
fswrqaafvdsycwaavqqknslqsesgnlplwlhkffpyilllfaillylpplfwrfaa
aphicsdlkfimeeldkvynraikaakpiveqylktkknsnnliikyiscrlltliiill
aciylgyyfslsslsdefvcsiksgilrndstvpdqfqckliavgifqllsvinlvvyvl
lapvvvytlfvpfrqktdvlkvyeilptfdvlhfksegyndlslynlfleenisevksyk
clkvleni