PDB entry 6lrt

View 6lrt on RCSB PDB site
Description: crystal structure of isocitrate lyase (caur_3889) from chloroflexus aurantiacus in complex with isocitrate and manganese ion
Deposited on 2020-01-16, released 2021-07-28
The last revision was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Chain 'D':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Chain 'G':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Chain 'J':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Chain 'M':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Chain 'P':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Chain 'S':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Chain 'V':
    Compound: isocitrate lyase
    Species: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [TaxId:324602]
    Gene: Caur_3889
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9WDE7 (12-435)
      • initiating methionine (0)
      • expression tag (1-11)
  • Heterogens: ICT, MN, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6lrtA (A:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtA (A:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6lrtD (D:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtD (D:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6lrtG (G:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtG (G:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6lrtJ (J:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtJ (J:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6lrtM (M:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtM (M:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6lrtP (P:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtP (P:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf

  • Chain 'S':
    Sequence, based on SEQRES records:
    >6lrtS (S:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtS (S:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf

  • Chain 'V':
    Sequence, based on SEQRES records:
    >6lrtV (V:)
mrgshhhhhhgsmdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmg
aerlwnllhtepyinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqsly
pansgpqlvrninnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayie
agaagvhfedqlasekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdana
atlltsdiderdrpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnlee
arrfaeaihaqfpgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfha
lnysmfelarnyrdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviagge
isttaltgsteeeqfh

    Sequence, based on observed residues (ATOM records):
    >6lrtV (V:)
mdraaqikqiadswntprfagivrpytpedvyrlrgsvqieytlarmgaerlwnllhtep
yinalgaltgnqamqqvkaglkaiylsgwqvaadanlagqmypdqslypansgpqlvrni
nnalrradqiyhsegrndiywfapivadaeagfggplnvfeimkayieagaagvhfedql
asekkcghmggkvliptqaairnlvaarlaadvmgvptiivartdanaatlltsdiderd
rpfctgertsegfyrvragldqaiarglayapyadmiwcetsepnleearrfaeaihaqf
pgkllayncspsfnwkkklddatiaafqrelgamgykfqfvtlagfhalnysmfelarny
rdrgmaayselqqaefaaeaygytatrhqrevgtgyfdevaqviaggeisttaltgstee
eqf