PDB entry 6lre

View 6lre on RCSB PDB site
Description: human cgas catalytic domain bound with compound 3
Deposited on 2020-01-16, released 2020-06-24
The last revision was dated 2021-10-13, with a file datestamp of 2021-10-08.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: CGAS, C6orf150, MB21D1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: CGAS, C6orf150, MB21D1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EQL, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6lreA (A:)
daapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyye
hvkisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskm
lskfrkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpastqe
glriqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktc
cenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwd
rkdlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnef
pvfdef

    Sequence, based on observed residues (ATOM records):
    >6lreA (A:)
gasklravleklklsrddvkgvvdhlllrlkcdsafrgvgllnehvkisapnefdvmfkl
evpriqleeysntrayyfvkfkenplsqflegeilsaskmlskfrkiikeeiimkrpavt
lliisvditlalesksswpastqeglriqnwlsakvrkqlrlkpfylvpkhaqeetwrls
fshiekeilnnhgksktccenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhv
ktaffhvctqnpqdsqwdrkdlglcfdncvtyflqclrteklenyfipefnlfssnlidk
rskefltkqieyernnefpvfd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6lreB (B:)
daapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyye
hvkisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskm
lskfrkiikeeindikdtdvimkrkrggspavtllisekisvditlalesksswpastqe
glriqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktc
cenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwd
rkdlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnef
pvfdef

    Sequence, based on observed residues (ATOM records):
    >6lreB (B:)
gasklravleklklsraagmvkgvvdhlllrlkcdsafrgvgllnyehvkisapnefdvm
fklevpriqleeysntrayyfvkfkenplsqflegeilsaskmlskfrkiikeeindidt
dvimkrkgsavtllisekisvditlalesksswpastqeglriqnwlsakvrkqlrlkpf
ylvpkhakgfqeetwrlsfshiekeilnnhgksktccenkeekccrkdclklmkylleql
kerfkdkkhldkfssyhvktaffhvctqnpqdsqwdrkdlglcfdncvtyflqclrtekl
enyfipefnlfssnlidkrskefltkqieyernnefpvfd