PDB entry 6lqx

View 6lqx on RCSB PDB site
Description: Crystal structure of the CBP bromodomain in complex with small molecule LC-CPin7
Class: transferase
Keywords: inhibitor, CBP, p300, Bromodomain, LC-CPin7, TRANSFERASE
Deposited on 2020-01-14, released 2021-01-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: XRAY
Resolution: 2.46 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: creb-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: Crebbp
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6lqxa_
  • Chain 'B':
    Compound: creb-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: Crebbp
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6lqxb_
  • Chain 'C':
    Compound: creb-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: Crebbp
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6lqxc_
  • Chain 'D':
    Compound: creb-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: Crebbp
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6lqxd_
  • Heterogens: EOO, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6lqxA (A:)
kkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrk
ldtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqsl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6lqxB (B:)
kkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrk
ldtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqsl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6lqxC (C:)
kkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrk
ldtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqsl

    Sequence, based on observed residues (ATOM records): (download) 
    >6lqxC (C:)
kpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrkldtg
qyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqsl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6lqxD (D:)
kkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrk
ldtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqsl

    Sequence, based on observed residues (ATOM records): (download) 
    >6lqxD (D:)
kifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrkl
dtgqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqsl