PDB entry 6lmx

View 6lmx on RCSB PDB site
Description: cryo-em structure of the calhm chimeric construct (9-mer)
Deposited on 2019-12-26, released 2020-07-29
The last revision was dated 2020-09-09, with a file datestamp of 2020-09-04.
Experiment type: EM
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALHM2, FAM26B
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6lmxA (A:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxA (A:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6lmxB (B:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxB (B:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6lmxC (C:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxC (C:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6lmxD (D:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxD (D:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6lmxE (E:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxE (E:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6lmxF (F:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxF (F:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6lmxG (G:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxG (G:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6lmxH (H:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxH (H:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6lmxI (I:)
mdkfrmmfqflqsnqesfmngicgimalasaqmyssfefscpcmpeynytygiglliipp
iwffllgfvlnnnvsvlaeewkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmd
gksflcafsinldiekfgnaslvigmteteklkflaripckdlfednevrvaatryikci
sqacgwmfllmmtftaflirairpcftqasyrqeaywaqyranedqlfqrtaevhsrvla
annvrrffgfvalnkddeelianfpvegtqprpqwnaitgvylyrenqglplysrlhkwa
qglagngaapdnvemallpsenlyfq

    Sequence, based on observed residues (ATOM records):
    >6lmxI (I:)
gicgimalasaqmyssfefscpcmpeynytygiglliippiwffllgfvlnnnvsvlaee
wkrptgrrtkdpsvlrymlcsitqrsliapavwvsvtlmdgksflcafsinldiekfgna
slvigmteteklkflaripckdlfednevrvaatryikcisqacgwmfllmmtftaflir
airpcftqasyrqeaywaqyranedqlfqrtaevhsrvlaannvrrffgfvalnkddeel