PDB entry 6lmi

View 6lmi on RCSB PDB site
Description: Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid
Class: transferase
Keywords: hydrolase transferase/inhibitor, TRANSFERASE
Deposited on 2019-12-25, released 2020-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Integrase catalytic
    Species: Human immunodeficiency virus type 1 group M subtype B (isolate NY5) [TaxId:11698]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497
      • engineered mutation (138)
    Domains in SCOPe 2.08: d6lmia_
  • Heterogens: EJ9, SO4, PGE, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6lmiA (A:)
gshmhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklag
rwpvktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvr
dqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6lmiA (A:)
dcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvh
tdngsnftsttvkaacwwagikqefgipsmnkelkkiigqvrdqaehlktavqmavfihn
kkrkgysagerivdiiatdiq