PDB entry 6lit

View 6lit on RCSB PDB site
Description: Estrogen-related receptor beta(ERR2) in complex with BPA
Class: transcription
Keywords: ERR2, Transcription factor, BPA, TRANSCRIPTION
Deposited on 2019-12-13, released 2020-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-07, with a file datestamp of 2020-10-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Steroid hormone receptor ERR2
    Species: Homo sapiens [TaxId:9606]
    Gene: ESRRB, ERRB2, ESRL2, NR3B2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95718
      • engineered mutation (152)
      • engineered mutation (178)
    Domains in SCOPe 2.08: d6lita_
  • Chain 'B':
    Compound: Steroid hormone receptor ERR2
    Species: Homo sapiens [TaxId:9606]
    Gene: ESRRB, ERRB2, ESRL2, NR3B2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95718
      • engineered mutation (152)
      • engineered mutation (178)
    Domains in SCOPe 2.08: d6litb_
  • Chain 'D':
    Compound: 10-mer from Nuclear receptor coactivator 2
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOA2, BHLHE75, SRC2, TIF2
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 10-mer from Nuclear receptor coactivator 2
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOA2, BHLHE75, SRC2, TIF2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 2OH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6litA (A:)
pakkpltkivshllvaepdklyampppgmpegdikalttlcdladrelvviigwakhipg
fsslslgdqmsllqsawmeililgivyrslpyddklvyaedyimdeehsrlagllelyra
ilqlvrrykklkvekeefvtlkalalansdsmhiedleavqklqdllhealqdyelsqhh
eepwrtgkllltlpllrqtaakavqhfysvklqgkvpmhklflemleakv

    Sequence, based on observed residues (ATOM records): (download) 
    >6litA (A:)
gdikalttlcdladrelvviigwakhipgfsslslgdqmsllqsawmeililgivyrslp
yddklvyaedyimdeehsrlagllelyrailqlvrrykklkvekeefvtlkalalansds
mhiedleavqklqdllhealqdyelsqhheepwrtgkllltlpllrqtaakavqhfysvk
lqgkvpmhklflemleak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6litB (B:)
pakkpltkivshllvaepdklyampppgmpegdikalttlcdladrelvviigwakhipg
fsslslgdqmsllqsawmeililgivyrslpyddklvyaedyimdeehsrlagllelyra
ilqlvrrykklkvekeefvtlkalalansdsmhiedleavqklqdllhealqdyelsqhh
eepwrtgkllltlpllrqtaakavqhfysvklqgkvpmhklflemleakv

    Sequence, based on observed residues (ATOM records): (download) 
    >6litB (B:)
gdikalttlcdladrelvviigwakhipgfsslslgdqmsllqsawmeililgivyrslp
yddklvyaedyimdeehsrlagllelyrailqlvrrykklkvekeefvtlkalalansds
mhiedleavqklqdllhealqdyelsqhheepwrtgkllltlpllrqtaakavqhfysvk
lqgkvpmhklflemlea

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.