PDB entry 6lhd

View 6lhd on RCSB PDB site
Description: crystal structure of p53/bcl-xl fusion complex
Deposited on 2019-12-07, released 2021-03-31
The last revision was dated 2021-05-26, with a file datestamp of 2021-05-21.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fusion protein of Bcl-2-like protein 1 and Isoform 6 of Cellular tumor antigen p53
    Species: Homo sapiens [TaxId:9606]
    Gene: p53
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817
      • linker (149)
      • linker (149)
      • linker (149)
      • linker (149)
      • linker (149)
      • linker (149)
    • Uniprot P04637
  • Chain 'B':
    Compound: fusion protein of Bcl-2-like protein 1 and Isoform 6 of Cellular tumor antigen p53
    Species: Homo sapiens [TaxId:9606]
    Gene: p53
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (Start-155)
      • linker (149)
      • linker (149)
      • linker (149)
      • linker (149)
      • linker (149)
      • linker (149-150)
      • linker (150)
      • linker (155)
      • linker (155)
      • linker (155)
      • linker (155)
      • linker (155)
      • linker (155)
    • Uniprot P04637 (155-End)
  • Heterogens: ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6lhdA (A:)
gpsqsnrelvvdflsyklsqkgyswsqfsdveenrteapegteseavkqalreagdefel
ryrrafsdltsqlhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkem
qvlvsriaawmatylndhlepwiqenggwdtfvelygnnaaaggggslvprgsggggssv
psqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstpppgtrv
ramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvv
vpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevrvcac
pgrdrrteeenlrkk

    Sequence, based on observed residues (ATOM records):
    >6lhdA (A:)
qsnrelvvdflsyklsqkgyswsavkqalreagdefelryrrlhitpgtayqsfeqvvne
ldgvnwgrivaffsfggalcvesvdkemqvlvsriaawmatylndhlepwiqenggwdsv
psqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstpppgtrv
ramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvv
vpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevrvcac
pgrdrrteeenl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6lhdB (B:)
gpsqsnrelvvdflsyklsqkgyswsqfsdveenrteapegteseavkqalreagdefel
ryrrafsdltsqlhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkem
qvlvsriaawmatylndhlepwiqenggwdtfvelygnnaaaggggslvprgsggggssv
psqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstpppgtrv
ramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvv
vpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevrvcac
pgrdrrteeenlrkk

    Sequence, based on observed residues (ATOM records):
    >6lhdB (B:)
qsnrelvvdflsyklsqkgyswsqfsdeavkqalreagdefelryrrafsdltsqlhitp
gtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawmatylnd
hlepwiqenggwdtfvelyvpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfcql
aktcpvqlwvdstpppgtrvramaiykqsqhmtevvrrcphhercsdsdglappqhlirv
egnlrveylddrntfrhsvvvpyeppevgsdcttihynymcnsscmggmnrrpiltiitl
edssgnllgrnsfevrvcacpgrdrrteeenl