PDB entry 6lg6

View 6lg6 on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with compound BDF-1021
Class: transcription
Keywords: BRD4, Inhibitor, Complex, DNA BINDING PROTEIN, TRANSCRIPTION
Deposited on 2019-12-04, released 2020-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-09, with a file datestamp of 2020-12-04.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d6lg6a1, d6lg6a2
  • Heterogens: EC9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6lg6A (A:)
mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
elpte

    Sequence, based on observed residues (ATOM records): (download) 
    >6lg6A (A:)
mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
elpt