PDB entry 6lb5

View 6lb5 on RCSB PDB site
Description: crystal structure of dimeric rxr-lbd complexed with full agonist net- 3ib and tif2 co-activator
Deposited on 2019-11-13, released 2020-11-18
The last revision was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: nuclear receptor coactivator 2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: nuclear receptor coactivator 2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: E80, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6lb5A (A:)
gsshssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftl
vewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahs
agvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyas
leayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaph
qmt

    Sequence, based on observed residues (ATOM records):
    >6lb5A (A:)
dmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvillragwn
elliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkte
lgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalr
siglkclehlfffkligdtpidtflmemlea

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6lb5B (B:)
khkilhrllqdss

    Sequence, based on observed residues (ATOM records):
    >6lb5B (B:)
hkilhrllqd

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6lb5C (C:)
gsshssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftl
vewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahs
agvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyas
leayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaph
qmt

    Sequence, based on observed residues (ATOM records):
    >6lb5C (C:)
dmpverileaelavepktetyveandpvtnicqaadkqlftlvewakriphfselplddq
villragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskm
rdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfak
lllrlpalrsiglkclehlfffkligdtpidtflmemlea

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6lb5D (D:)
khkilhrllqdss

    Sequence, based on observed residues (ATOM records):
    >6lb5D (D:)
khkilhrllqd