PDB entry 6la7

View 6la7 on RCSB PDB site
Description: Cryo-EM structure of echovirus 11 complexed with its uncoating receptor FcRn at pH 5.5
Class: virus
Keywords: Cryo-EM structure, echovirus 11, FcRn, pH 5.5, VIRUS
Deposited on 2019-11-12, released 2020-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-07, with a file datestamp of 2020-10-02.
Experiment type: EM
Resolution: 2.82 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Capsid protein VP1
    Species: Echovirus E11 [TaxId:12078]
    Database cross-references and differences (RAF-indexed):
    • PDB 6LA7 (0-284)
    Domains in SCOPe 2.08: d6la7a_
  • Chain 'B':
    Compound: capsid protein VP2
    Species: Echovirus E11 [TaxId:12078]
    Database cross-references and differences (RAF-indexed):
    • PDB 6LA7 (0-250)
  • Chain 'C':
    Compound: capsid protein vp3
    Species: Echovirus E11 [TaxId:12078]
    Database cross-references and differences (RAF-indexed):
    • PDB 6LA7 (0-237)
    Domains in SCOPe 2.08: d6la7c_
  • Chain 'D':
    Compound: capsid protein VP4
    Species: Echovirus E11 [TaxId:12078]
    Database cross-references and differences (RAF-indexed):
    • PDB 6LA7 (0-69)
  • Chain 'E':
    Compound: igg receptor fcrn large subunit p51
    Species: Homo sapiens [TaxId:9606]
    Gene: FCRN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6la7e1, d6la7e2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6la7f_

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6la7A (A:)
    vveavenavarvadtissgpsnsqavpaltavetghtsqvtpsdtiqtrhvrnyhsrses
    sienflcrsacvymgeyhttntdtsklfaswtinarrmvqmrrklelftyvrfdmevtfv
    itskqdqgtqlgqdmpplthqimyippggpipksvtdytwqtstnpsifwtegnapprms
    ipfisignaysnfydgwshfsqngvygyntlnhmgqiyvrhvngssplpmtstvrmyfkp
    khvkvwvprpprlcqyknastvnftptnitekrqsinyipetvkp
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6la7C (C:)
    glpvmntpgsnqfltsddfqspsampqfdvtpelnipgevqnlmeiaevdsvvpvnnveg
    kldtmeiyripvqsgnhqssqvfgfqvqpgldnvfkhtllgeilnyyahwsgsikltfvf
    cgsamatgkfllayappganapksrkdamlgthiiwdvglqsscvlcipwisqthyrlvq
    qdeytsagnvtcwyqtgivvpagtptscsimcfvsacndfsvrllkdtpfieqsallq
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6la7E (E:)
    lsllyhltavsspapgtpafwvsgwlgpqqylsynslrgeaepcgawvwenqvswyweke
    ttdlrikeklfleafkalggkgpytlqgllgcelgpdntsvptakfalngeefmnfdlkq
    gtwggdwpealaisqrwqqqdkaankeltfllfscphrlrehlergrgnlewkeppsmrl
    karpsspgfsvltcsafsfyppelqlrflrnglaagtgqgdfgpnsdgsfhasssltvks
    gdehhyccivqhaglaqplrvel
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6la7F (F:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm