PDB entry 6l69

View 6l69 on RCSB PDB site
Description: Crystal structure of CYP154C2 from Streptomyces avermitilis
Class: oxidoreductase
Keywords: Cytochrome P450, substrate-free, hydroxylase, OXIDOREDUCTASE
Deposited on 2019-10-28, released 2020-09-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 hydroxylase
    Species: Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) [TaxId:227882]
    Gene: cyp19, SAVERM_3882
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6l69a_
  • Chain 'B':
    Compound: Cytochrome P450 hydroxylase
    Species: Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) [TaxId:227882]
    Gene: cyp19, SAVERM_3882
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6l69b_
  • Heterogens: HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6l69A (A:)
mgsshhhhhhssglvprgshmttrialdpfvsdleaesaalraagplaavelpggvpvwa
vthhaeakklltdprlvkdinvwgawqrgeiapdwpliglanpgrsmltvdgadhrrmrt
lvaqaltprrveqmreritklteelldrltgevvdlkadfayplpmyvvadlmgidearl
prlgelfekffstqtppaeviatltelagimaetvaakraapgddltsalilasedgdhl
tdaeivstlqlmvaaghettislivnavvnlsthpeqralvlsgeadwssvveetlryst
ptshvlirfatedvpvgdkvlpagdalivsygalgrdeaahgptagefditrstenrhis
fghgphvcpgaalsrleagvalpalyarfpkldlavpaaelrnkpvvtqndlfelpvrlg

    Sequence, based on observed residues (ATOM records): (download) 
    >6l69A (A:)
trialdpfvsdleaesaalraagplaavelpggvpvwavthhaeakklltdprlvkdinv
wgawqrgeiapdwpliglanpgrsmltvdgadhrrmrtlvaqaltprrveqmreritklt
eelldrltgevvdlkadfayplpmyvvadlmgidearlprlgelfekffstqtppaevia
tltelagimaetvaakraapgddltsalilasedgdhltdaeivstlqlmvaaghettis
livnavvnlsthpeqralvlsgeadwssvveetlrystptshvlirfatedvpvgdkvlp
agdalivsygalgrdeaahgptagefditrstenrhisfghgphvcpgaalsrleagval
palyarfpkldlavpaaelrnkpvvtqndlfelpvrlg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6l69B (B:)
mgsshhhhhhssglvprgshmttrialdpfvsdleaesaalraagplaavelpggvpvwa
vthhaeakklltdprlvkdinvwgawqrgeiapdwpliglanpgrsmltvdgadhrrmrt
lvaqaltprrveqmreritklteelldrltgevvdlkadfayplpmyvvadlmgidearl
prlgelfekffstqtppaeviatltelagimaetvaakraapgddltsalilasedgdhl
tdaeivstlqlmvaaghettislivnavvnlsthpeqralvlsgeadwssvveetlryst
ptshvlirfatedvpvgdkvlpagdalivsygalgrdeaahgptagefditrstenrhis
fghgphvcpgaalsrleagvalpalyarfpkldlavpaaelrnkpvvtqndlfelpvrlg

    Sequence, based on observed residues (ATOM records): (download) 
    >6l69B (B:)
trialdpfvsdleaesaalraagplaavelpggvpvwavthhaeakklltdprlvkdinv
wgawqrgeiapdwpliglanpgrsmltvdgadhrrmrtlvaqaltprrveqmreritklt
eelldrltgevvdlkadfayplpmyvvadlmgidearlprlgelfekffstqtppaevia
tltelagimaetvaakraapgddltsalilasedgdhltdaeivstlqlmvaaghettis
livnavvnlsthpeqralvlsgeadwssvveetlrystptshvlirfatedvpvgdkvlp
agdalivsygalgrdeaahgptagefditrstenrhisfghgphvcpgaalsrleagval
palyarfpkldlavpaaelrnkpvvtqndlfelpvrlg