PDB entry 6l38

View 6l38 on RCSB PDB site
Description: X-ray structure of human PPARalpha ligand binding domain-GW9662-gemfibrozil co-crystals obtained by delipidation and co-crystallization
Class: transcription
Keywords: Nuclear receptor, Protein-ligand complex, PPAR, Transcription
Deposited on 2019-10-09, released 2020-11-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 2.76 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07869 (4-272)
      • expression tag (3)
    Domains in SCOPe 2.08: d6l38a1, d6l38a2
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07869 (4-272)
      • expression tag (3)
    Domains in SCOPe 2.08: d6l38b1, d6l38b2
  • Heterogens: GW9

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6l38A (A:)
gshmtadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlv
aklvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvye
aifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdi
slfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrq
lvtehaqlvqiikktesdaalhpllqeiyrdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >6l38A (A:)
mtadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvakl
vangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaif
amlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislf
vaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvt
ehaqlvqiikktesdaalhpllqeiyrdmy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6l38B (B:)
gshmtadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlv
aklvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvye
aifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdi
slfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrq
lvtehaqlvqiikktesdaalhpllqeiyrdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >6l38B (B:)
mtadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvakl
vangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaif
amlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislf
vaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvt
ehaqlvqiikktesdaalhpllqeiyrdmy