PDB entry 6l24

View 6l24 on RCSB PDB site
Description: Crystal structure of CK2a1 H115Y/V116I with hematein
Class: transferase
Keywords: protein kinase, transferase, inhibitor, complex
Deposited on 2019-10-02, released 2020-02-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-26, with a file datestamp of 2020-02-21.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A1, CK2A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68400 (Start-339)
      • engineered mutation (119-120)
    Domains in SCOPe 2.08: d6l24a_
  • Heterogens: E3U, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6l24A (A:)
gplgsmsgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfe
ainitnnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfey
inntdfkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlid
wglaefyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhg
hdnydqlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvsp
ealdfldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >6l24A (A:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfeyinntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqarmg