PDB entry 6l0j

View 6l0j on RCSB PDB site
Description: Crystal structure of Dihydroorotase in complex with malate at pH7.5 from Saccharomyces cerevisiae
Class: hydrolase
Keywords: Dihydropyrimidinase Dihydroorotase metalloenzyme, HYDROLASE
Deposited on 2019-09-26, released 2020-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6l0ja_
  • Chain 'B':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20051 (Start-363)
      • expression tag (364)
    Domains in SCOPe 2.08: d6l0jb1, d6l0jb2
  • Chain 'C':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6l0jc_
  • Chain 'D':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20051 (Start-363)
      • expression tag (364)
    Domains in SCOPe 2.08: d6l0jd1, d6l0jd2
  • Heterogens: LMR, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6l0jA (A:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0jA (A:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
epr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6l0jB (B:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0jB (B:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
eprl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6l0jC (C:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0jC (C:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
epr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6l0jD (D:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0jD (D:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
eprl