PDB entry 6l0i

View 6l0i on RCSB PDB site
Description: Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae
Class: hydrolase
Keywords: Dihydropyrimidinase Dihydroorotase metalloenzyme, HYDROLASE
Deposited on 2019-09-26, released 2020-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20051 (Start-363)
      • expression tag (364)
    Domains in SCOPe 2.08: d6l0ia1, d6l0ia2
  • Chain 'B':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6l0ib_
  • Chain 'C':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20051 (Start-363)
      • expression tag (364)
    Domains in SCOPe 2.08: d6l0ic1, d6l0ic2
  • Chain 'D':
    Compound: dihydroorotase
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: URA4, YLR420W, L9931.1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20051 (Start-363)
      • expression tag (364)
    Domains in SCOPe 2.08: d6l0id1, d6l0id2
  • Heterogens: LMR, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6l0iA (A:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0iA (A:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
eprl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6l0iB (B:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0iB (B:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
epr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6l0iC (C:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0iC (C:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
eprl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6l0iD (D:)
mvqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykkt
lqklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsaf
ypifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiileh
ctsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkk
alvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenl
kgfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvr
weprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6l0iD (D:)
vqeidlgltcdmhvhvregamcelvtpkirdggvsiayimpnlqppittldrvieykktl
qklapkttflmsfylskdltpdliheaaqqhairgvkcypagvttnsaagvdpndfsafy
pifkamqeenlvlnlhgekpsvhdgdkepihvlnaeeaflpalkklhndfpnlkiilehc
tsesaiktiedinknvkkatdvkvaatltahhlfltiddwagnpvnfckpvaklpndkka
lvkaavsgkpyfffgsdsaphpvqnkanyegvcagvysqsfaipyiaqvfeeqnalenlk
gfvsdfgisfyevkdsevassdkailfkkeqvipqvisdgkdisiipfkagdklswsvrw
eprl