PDB entry 6kz0

View 6kz0 on RCSB PDB site
Description: HRV14 3C in complex with single chain antibody GGVV
Class: viral protein
Keywords: protease, inhibitor, complex structure, VIRAL PROTEIN
Deposited on 2019-09-21, released 2020-05-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-01, with a file datestamp of 2020-06-26.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Genome polyprotein
    Species: Human rhinovirus 14 [TaxId:12131]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03303 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6kz0a1, d6kz0a2
  • Chain 'B':
    Compound: GGVV H chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0
    Domains in SCOPe 2.08: d6kz0b_
  • Chain 'C':
    Compound: GGVV L chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0 (0-End)
    Domains in SCOPe 2.08: d6kz0c_
  • Chain 'D':
    Compound: Genome polyprotein
    Species: Human rhinovirus 14 [TaxId:12131]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03303 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6kz0d1, d6kz0d2
  • Chain 'E':
    Compound: GGVV H chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0
    Domains in SCOPe 2.08: d6kz0e_
  • Chain 'F':
    Compound: GGVV L chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0 (0-End)
    Domains in SCOPe 2.08: d6kz0f_
  • Chain 'G':
    Compound: Genome polyprotein
    Species: Human rhinovirus 14 [TaxId:12131]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03303 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6kz0g1, d6kz0g2
  • Chain 'H':
    Compound: GGVV H chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0
    Domains in SCOPe 2.08: d6kz0h_
  • Chain 'I':
    Compound: GGVV L chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0 (0-End)
    Domains in SCOPe 2.08: d6kz0i_
  • Chain 'J':
    Compound: Genome polyprotein
    Species: Human rhinovirus 14 [TaxId:12131]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03303 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6kz0j1, d6kz0j2
  • Chain 'K':
    Compound: GGVV H chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0
    Domains in SCOPe 2.08: d6kz0k_
  • Chain 'L':
    Compound: GGVV L chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KZ0 (0-End)
    Domains in SCOPe 2.08: d6kz0l_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6kz0A (A:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvdpeninleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpv
tmaglinlsstptnrmirydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyf
vekq

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0A (A:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpvtmarmi
rydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyfv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6kz0B (B:)
gammaqvqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvf
dtlkyaqrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqg
tlvtvssggggsggggsggggs

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0B (B:)
vqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvfdtlkya
qrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqgtlvtvs
s

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6kz0C (C:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdikr

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0C (C:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdik

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6kz0D (D:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvdpeninleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpv
tmaglinlsstptnrmirydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyf
vekq

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0D (D:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpvtmarmi
rydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyfv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6kz0E (E:)
gammaqvqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvf
dtlkyaqrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqg
tlvtvssggggsggggsggggs

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0E (E:)
qvqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvfdtlky
aqrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqgtlvtv
ss

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6kz0F (F:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdikr

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0F (F:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdik

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6kz0G (G:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvdpeninleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpv
tmaglinlsstptnrmirydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyf
vekq

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0G (G:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpvtmrmir
ydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyfv

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6kz0H (H:)
gammaqvqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvf
dtlkyaqrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqg
tlvtvssggggsggggsggggs

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0H (H:)
qvqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvfdtlky
aqrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqgtlvtv
ss

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6kz0I (I:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdikr

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0I (I:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdik

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6kz0J (J:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvdpeninleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpv
tmaglinlsstptnrmirydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyf
vekq

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0J (J:)
gsgpntefalsllrknimtittskgeftglgihdrvcvipthaqpgddvlvngqkirvkd
kyklvdleltvltldrnekfrdirgfisedlegvdatlvvhsnnftntilevgpvtmarm
irydyatktgqcggvlcatgkifgihvggngrqgfsaqlkkqyfv

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6kz0K (K:)
gammaqvqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvf
dtlkyaqrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqg
tlvtvssggggsggggsggggs

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0K (K:)
qvqlvqsgaevkqpgssvkvscktsgdifstygfnwvrqapgqglewmggiapvfdtlky
aqrfqgrllitadesatsvymelsslrsddtavyycaragqggvvgnyldywgqgtlvtv
ss

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6kz0L (L:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdikr

    Sequence, based on observed residues (ATOM records): (download) 
    >6kz0L (L:)
diqmtqspsslsasvgdrvtitcrasqgisnylawyqqkpgkvpklliyaastlqsgvps
rfsgsgsgtdftltisslqpedvatyycqkynsapltfgqgtkvdik