PDB entry 6kyr

View 6kyr on RCSB PDB site
Description: Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain
Class: signaling protein
Keywords: kinase, autoinhibition, SIGNALING PROTEIN
Deposited on 2019-09-20, released 2020-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase DCLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCLK1, DCAMKL1, DCDC3A, KIAA0369
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6kyra_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase DCLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: DCLK1, DCAMKL1, DCDC3A, KIAA0369
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6kyrb_
  • Heterogens: BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6kyrA (A:)
gsgfqipatiterykvgrtigdgnfavvkecverstareyalkiikkskcrgkehmiqne
vsilrrvkhpnivllieemdvptelylvmelvkggdlfdaitstnkyterdasgmlynla
saikylhslnivhrdikpenllvyehqdgskslklgdfglativdgplytvcgtptyvap
eiiaetgyglkvdiwaagvityillcgfppfrgsgddqevlfdqilmgqvdfpspywdnv
sdsakelitmmllvdvdqrfsavqvlehpwvnddglpenehqlsvagkikkhfntgpkln
staagvsviattaldkerqvfrrrrnqd

    Sequence, based on observed residues (ATOM records): (download) 
    >6kyrA (A:)
fqipatiterykvgrtigdgnfavvkecverstareyalkiikkskcrgkehmiqnevsi
lrrvkhpnivllieemdvptelylvmelvkggdlfdaitstnkyterdasgmlynlasai
kylhslnivhrdikpenllvyehqdgskslklgdfglativdgplytvcgtptyvapeii
aetgyglkvdiwaagvityillcgfppfrgdqevlfdqilmgqvdfpspywdnvsdsake
litmmllvdvdqrfsavqvlehpwvnddglpenehqlsvagkikkhftaagvsviattal
dkerqvfrrrr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6kyrB (B:)
gsgfqipatiterykvgrtigdgnfavvkecverstareyalkiikkskcrgkehmiqne
vsilrrvkhpnivllieemdvptelylvmelvkggdlfdaitstnkyterdasgmlynla
saikylhslnivhrdikpenllvyehqdgskslklgdfglativdgplytvcgtptyvap
eiiaetgyglkvdiwaagvityillcgfppfrgsgddqevlfdqilmgqvdfpspywdnv
sdsakelitmmllvdvdqrfsavqvlehpwvnddglpenehqlsvagkikkhfntgpkln
staagvsviattaldkerqvfrrrrnqd

    Sequence, based on observed residues (ATOM records): (download) 
    >6kyrB (B:)
fqipatiterykvgrtigdgnfavvkecverstareyalkiikkskcrgkehmiqnevsi
lrrvkhpnivllieemdvptelylvmelvkggdlfdaitstnkyterdasgmlynlasai
kylhslnivhrdikpenllvyehqdgskslklgdfglativdgplytvcgtptyvapeii
aetgyglkvdiwaagvityillcgfppfrgdqevlfdqilmgqvdfpspywdnvsdsake
litmmllvdvdqrfsavqvlehpwvnddglpenehqlsvagkikkhftaagvsviattal
dkerqvfrrr