PDB entry 6kx8

View 6kx8 on RCSB PDB site
Description: Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
Class: circadian clock protein
Keywords: circadian clock protein
Deposited on 2019-09-10, released 2020-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-06-03, with a file datestamp of 2020-05-29.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cryptochrome-2
    Species: Mus musculus [TaxId:10090]
    Gene: Cry2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6kx8a1, d6kx8a2
  • Chain 'B':
    Compound: Cryptochrome-2
    Species: Mus musculus [TaxId:10090]
    Gene: Cry2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6kx8b1, d6kx8b2
  • Heterogens: DYX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6kx8A (A:)
gtmaaaavvaatvpaqsmgadgassvhwfrkglrlhdnpallaavrgarcvrcvyildpw
faasssvginrwrfllqsledldtslrklnsrlfvvrgqpadvfprlfkewgvtrltfey
dsepfgkerdaaimkmakeagvevvtenshtlydldriielngqkppltykrfqalisrm
elpkkpavavssqqmescraeiqenhddtygvpsleelgfpteglgpavwqggetealar
ldkhlerkawvanyerprmnansllasptglspylrfgclscrlfyyrlwdlykkvkrns
tpplslfgqllwreffytaatnnprfdrmegnpiciqipwdrnpealakwaegktgfpwi
daimtqlrqegwihhlarhavacfltrgdlwvswesgvrvfdellldadfsvnagswmwl
scsaffqqffhcycpvgfgrrtdpsgdyirrylpklkgfpsryiyepwnapesvqkaakc
iigvdyprpivnhaetsrlniermkqiyqqlsry

    Sequence, based on observed residues (ATOM records): (download) 
    >6kx8A (A:)
gassvhwfrkglrlhdnpallaavrgarcvrcvyildpsvginrwrfllqsledldtslr
klnsrlfvvrgqpadvfprlfkewgvtrltfeydsepfgkerdaaimkmakeagvevvte
nshtlydldriielngqkppltykrfqalisrmelpkkpavavssqqmescraeiqenhd
dtygvpsleelgfpteglgpavwqggetealarldkhlemnansllasptglspylrfgc
lscrlfyyrlwdlykkvkrnstpplslfgqllwreffytaatnnprfdrmegnpiciqip
wdrnpealakwaegktgfpwidaimtqlrqegwihhlarhavacfltrgdlwvswesgvr
vfdellldadfsvnagswmwlscsaffqqffhcycpvgfgrrtdpsgdyirrylpklkgf
psryiyepwnapesvqkaakciigvdyprpivnhaetsrlniermkqiy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6kx8B (B:)
gtmaaaavvaatvpaqsmgadgassvhwfrkglrlhdnpallaavrgarcvrcvyildpw
faasssvginrwrfllqsledldtslrklnsrlfvvrgqpadvfprlfkewgvtrltfey
dsepfgkerdaaimkmakeagvevvtenshtlydldriielngqkppltykrfqalisrm
elpkkpavavssqqmescraeiqenhddtygvpsleelgfpteglgpavwqggetealar
ldkhlerkawvanyerprmnansllasptglspylrfgclscrlfyyrlwdlykkvkrns
tpplslfgqllwreffytaatnnprfdrmegnpiciqipwdrnpealakwaegktgfpwi
daimtqlrqegwihhlarhavacfltrgdlwvswesgvrvfdellldadfsvnagswmwl
scsaffqqffhcycpvgfgrrtdpsgdyirrylpklkgfpsryiyepwnapesvqkaakc
iigvdyprpivnhaetsrlniermkqiyqqlsry

    Sequence, based on observed residues (ATOM records): (download) 
    >6kx8B (B:)
gassvhwfrkglrlhdnpallaavrgarcvrcvyildpwfaasssvginrwrfllqsled
ldtslrklnsrlfvvrgqpadvfprlfkewgvtrltfeydsepfgkerdaaimkmakeag
vevvtenshtlydldriielngqkppltykrfqalisrmelpkkpavavssqqmescrae
iqenhddtygvpsleelgfpteglgpavwqggetealarldkhlerkansllasptglsp
ylrfgclscrlfyyrlwdlykkvkstpplslfgqllwreffytaatnnprfdrmegnpic
iqipwdrnpealakwaegktgfpwidaimtqlrqegwihhlarhavacfltrgdlwvswe
sgvrvfdellldadfsvnagswmwlscsaffqqffhcycpvgfgrrtdpsgdyirrylpk
lkgfpsryiyepwnapesvqkaakciigvdyprpivnhaetsrlniermkq