PDB entry 6kvx

View 6kvx on RCSB PDB site
Description: crystal structure of the n-terminal domain single mutant (d119a) of the human mitochondrial calcium uniporter fused with t4 lysozyme
Deposited on 2019-09-05, released 2020-05-27
The last revision was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Endolysin,Calcium uniporter protein, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MCU, C10orf42, CCDC109A
    Database cross-references and differences (RAF-indexed):
    • Uniprot D9IEF7 (0-160)
      • engineered mutation (19)
      • engineered mutation (53)
      • engineered mutation (96)
      • linker (161-162)
    • Uniprot Q8NE86 (163-252)
      • engineered mutation (207)
  • Heterogens: SO4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6kvxA (A:)
mnifemlrideglrlkiykntegyytigighlltkspslnaakseldkaigrntngvitk
deaeklfnqdvdaavrgilrnaklkpvydsldavrraalinmvfqmgetgvagftnslrm
lqqkrwdeaavnlaksrwynqtpnrakrvittfrtgtwdaygsvtvvyqnglpvisvrlp
srrercqftlkpisdsvgvflrqlqeeargidrvaiyspdgvrvaastgidllllddfkl
vindltyhvrppklehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6kvxA (A:)
mnifemlrideglrlkiykntegyytigighlltkspslnaakseldkaigrntngvitk
deaeklfnqdvdaavrgilrnaklkpvydsldavrraalinmvfqmgetgvagftnslrm
lqqkrwdeaavnlaksrwynqtpnrakrvittfrtgtwdaygsvtvvyqnglpvisvrlp
srrercqftlkpisdsvgvflrqlqeeargidrvaiyspdgvrvaastgidllllddfkl
vindltyhvrppk