PDB entry 6kuc

View 6kuc on RCSB PDB site
Description: Crystal structure of Plasmodium falciparum histo-aspartic protease (HAP) zymogen (Form 2)
Class: hydrolase
Keywords: Histo-Aspartic protease, HAP, Plasmepsin, Proplasmepsin, Zymogen, Aspartic Protease, HYDROLASE
Deposited on 2019-08-31, released 2020-05-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-03, with a file datestamp of 2021-01-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HAP protein
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: hap
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y006 (128-379)
      • expression tag (3-4)
    Domains in SCOPe 2.08: d6kuca1, d6kuca2
  • Heterogens: PEG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6kucA (A:)
aisdpkystvgfniensydrlmktikehklknyikesvklfnkgltkksylgsefdnvel
kdlanvlsfgeaklgdngqkfnflfhtassnvwvpsikctsescesknhydssksktyek
ddtpvkltskagtisgifskdlvtigklsvpykfiemteivgfepfysesdvdgvfglgw
kdlsigsidpyivelktqnkieqavysiylppenknkgyltiggieerffdgplnyekln
hdlmwqvdldvhfgnvsskkanvildsatsvitvpteffnqfvesasvfkvpflslyvtt
cgntklptleyrspnkvytlepkqyleplenifsalcmlnivpidlekntfvlgdpfmrk
yftvydydnhtvgfalaknl

    Sequence, based on observed residues (ATOM records): (download) 
    >6kucA (A:)
dpkystvgfniensydrlmktikehklknyikesvklfnkgltkksylgsefdnvelkdl
anvlsfgeaklgdngqkfnflfhtassnvwvpsikctsescesknhydssksktyekddt
pvkltskagtisgifskdlvtigklsvpykfiemteivgfepfysesdvdgvfglgwkdl
sigsidpyivelktqnkieqavysiylppenknkgyltiggieerffdgplnyeklnhdl
mwqvdldvhfgnvsskkanvildsatsvitvpteffnqfvesasvfkvpflslyvttcgn
tklptleyrspnkvytlepkqyleplenifsalcmlnivpidlekntfvlgdpfmrkyft
vydydnhtvgfalaknl