PDB entry 6kn9

View 6kn9 on RCSB PDB site
Description: crystal structure of human interleukin 18 receptor beta extracellular domain in complex with an antagonistic scfv
Deposited on 2018-05-18, released 2020-02-12
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-02.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interleukin-18 receptor accessory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: IL18RAP, IL1R7
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Interleukin-18 receptor accessory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: IL18RAP, IL1R7
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Interleukin-18 receptor accessory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: IL18RAP, IL1R7
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ScFv
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KN9 (0-End)
  • Chain 'E':
    Compound: ScFv
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KN9
  • Chain 'F':
    Compound: ScFv
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6KN9
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6kn9A (A:)
fnisgcstkkllwtystrseeefvlfcdlpepqkshfchrnrlspkqvpehlpfmgsndl
sdvqwyqqpsngdpledirksyphiiqdkctlhfltpgvnnsgsyicrpkmikspydvac
cvkmilevkpqtnasceysashkqdlllgstgsiscpslscqsdaqspavtwykngklls
versnrivvdevydyhqgtyvcdytqsdtvsswtvravvqvrtivgdtklkpdildpved
tlevelgkpltisckarfgfervfnpvikwyikdsdlewevsvpeaksikstlkdeiier
niilekvtqrdlrrkfvcfvqnsignttqsvqlkekr

    Sequence, based on observed residues (ATOM records):
    >6kn9A (A:)
kkllwtystrseeefvlfcdlpepediksyphiiqdkctlhfltnnsgsyicrccvkmil
evkpqtnasashkqdlllgstgsiscpslsspavtwykngkllsversnrivvdevydyh
qgtyvcdytqsdtvsswtvravvqvrtivgdtklkpdildpvedtlevelgkpltiscka
rfgfervfnpvikwyikdsdlewevsvpeaksikstlkdeiierniilekvtqrdlrrkf
vcfvqnsignttqsvqlkek

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6kn9B (B:)
fnisgcstkkllwtystrseeefvlfcdlpepqkshfchrnrlspkqvpehlpfmgsndl
sdvqwyqqpsngdpledirksyphiiqdkctlhfltpgvnnsgsyicrpkmikspydvac
cvkmilevkpqtnasceysashkqdlllgstgsiscpslscqsdaqspavtwykngklls
versnrivvdevydyhqgtyvcdytqsdtvsswtvravvqvrtivgdtklkpdildpved
tlevelgkpltisckarfgfervfnpvikwyikdsdlewevsvpeaksikstlkdeiier
niilekvtqrdlrrkfvcfvqnsignttqsvqlkekr

    Sequence, based on observed residues (ATOM records):
    >6kn9B (B:)
kllwtystreeefvlfcdlhiiqdkctlhfltnnsgsyicrpkmikccvkmilevkpqdl
llgstgsiscpslsavtwykngklnrivvdevydyhqgtyvcswtvvqvrtivdtklkpd
ildpvedtlevelgkpltisckarfgfervfnpvikwyikdsdlewevsvpeaksikstl
kdeiierniilekvtqrdlrrkfvcfvqnsignttqsvqlkekr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6kn9C (C:)
fnisgcstkkllwtystrseeefvlfcdlpepqkshfchrnrlspkqvpehlpfmgsndl
sdvqwyqqpsngdpledirksyphiiqdkctlhfltpgvnnsgsyicrpkmikspydvac
cvkmilevkpqtnasceysashkqdlllgstgsiscpslscqsdaqspavtwykngklls
versnrivvdevydyhqgtyvcdytqsdtvsswtvravvqvrtivgdtklkpdildpved
tlevelgkpltisckarfgfervfnpvikwyikdsdlewevsvpeaksikstlkdeiier
niilekvtqrdlrrkfvcfvqnsignttqsvqlkekr

    Sequence, based on observed residues (ATOM records):
    >6kn9C (C:)
kllwtystrseeefvlfcdlpepqkshrksyphiiqdkctlhfltnsgsyicrpkmccvk
milevkpqtsashkqdlllgstgsiscpslspavtwykngkllsversnrivvdevydyh
qgtyvcdytqsdtvsswtvravvqvrtivgdtklkpdildpvedtlevelgkpltiscka
rfgfervfnpvikwyikdsdlewevsvpeaksikstlkdeiierniilekvtqrdlrrkf
vcfvqnsignttqsvqlkekr

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6kn9D (D:)
gpldpevqlvesggglvqpggslrlscaasgfnlyyssmhwvrqapgkglewvasiyssy
gytyyadsvkgrftisadtskntaylqmnslraedtavyycarssfshgygwygldywgq
gtlvtvssssggggsggggsggggsdiqmtqspsslsasvgdrvtitcrasqsvssavaw
yqqkpgkapklliysasslysgvpsrfsgsrsgtdftltisslqpedfatyycqqygyhy
aglitfgqgtkveikrt

    Sequence, based on observed residues (ATOM records):
    >6kn9D (D:)
gpldpevqlvesggglvqpggslrlscaasgfnlyyssmhwvrqapgkglewvasiyssy
gytyyadsvkgrftisadtskntaylqmnslraedtavyycarssfshgygwygldywgq
gtlvtvpsslsasvgdrvtitcrassavawyqqkpgkapklliysasslysgvpsrfsgs
rsgtdftltisslqpedfatyycqqygyaglitfgqgtkv

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6kn9E (E:)
gpldpevqlvesggglvqpggslrlscaasgfnlyyssmhwvrqapgkglewvasiyssy
gytyyadsvkgrftisadtskntaylqmnslraedtavyycarssfshgygwygldywgq
gtlvtvssssggggsggggsggggsdiqmtqspsslsasvgdrvtitcrasqsvssavaw
yqqkpgkapklliysasslysgvpsrfsgsrsgtdftltisslqpedfatyycqqygyhy
aglitfgqgtkveikrt

    Sequence, based on observed residues (ATOM records):
    >6kn9E (E:)
dpevqlvesscaasgfnlyyssmhwvrqkglsiyssygyttisadtskntaylqmedtav
yycarssfshgygwygldywgqgsvgvawyqqkapklliysasslysgvpgsrsgtslqp
edfatyycqliqgt

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6kn9F (F:)
gpldpevqlvesggglvqpggslrlscaasgfnlyyssmhwvrqapgkglewvasiyssy
gytyyadsvkgrftisadtskntaylqmnslraedtavyycarssfshgygwygldywgq
gtlvtvssssggggsggggsggggsdiqmtqspsslsasvgdrvtitcrasqsvssavaw
yqqkpgkapklliysasslysgvpsrfsgsrsgtdftltisslqpedfatyycqqygyhy
aglitfgqgtkveikrt

    Sequence, based on observed residues (ATOM records):
    >6kn9F (F:)
evqlvesggglvqpggslrlscaasgfnlyyssmhwvrqapgkglewvasiyssygytyy
adsvkgrftisadtskntaylqmnslraedtavyycarssfshgygwygldywgqgtlvt
vspsslsasvgdrvtitcrasssavawyqqkpgkapklliysasslysgvpsrfsgsrsg
tdftltisslqpedfatyycqqygyaglitfgqgtkveikr