PDB entry 6kmu

View 6kmu on RCSB PDB site
Description: p22/p10 complex of caspase-11 mutant c254a
Deposited on 2019-08-01, released 2020-03-11
The last revision was dated 2020-03-25, with a file datestamp of 2020-03-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P70343 (0-183)
      • engineered mutation (152)
  • Chain 'B':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P70343 (0-184)
      • engineered mutation (153)
  • Chain 'D':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P70343 (0-183)
      • engineered mutation (152)
  • Chain 'F':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P70343 (0-153)
      • engineered mutation (153)
  • Chain 'H':
    Compound: Caspase-4
    Species: Mus musculus [TaxId:10090]
    Gene: Casp4, Casp11, Caspl, Ich3
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6kmuA (A:)
lklcspeeftrlcrektqeiypikeangrtrkaliicntefkhlslryganfdiigmkgl
ledlgydvvvkeeltaegmesemkdfaalsehqtsdstflvlmshgtlhgicgtmhsekt
pdvlqydtiyqifnnchcpglrdkpkviivqaarggnsgemwiresskpqlcrgvdlprn
mead

    Sequence, based on observed residues (ATOM records):
    >6kmuA (A:)
lklcspeeftrlcrektqeiypikeangrtrkaliicntefkhlslryganfdiigmkgl
ledlgydvvvkeeltaegmesemkdfaalsehqtsdstflvlmshgtlhgicgtmhsekt
pdvlqydtiyqifnnchcpglrdkpkviivqaarggnsgemwirlprnmead

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6kmuB (B:)
klshvekdfiafysttphhlsyrdktggsyfitrliscfrkhacschlfdiflkvqqsfe
kasihsqmptidratltryfylfpgn

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6kmuC (C:)
tlklcspeeftrlcrektqeiypikeangrtrkaliicntefkhlslryganfdiigmkg
lledlgydvvvkeeltaegmesemkdfaalsehqtsdstflvlmshgtlhgicgtmhsek
tpdvlqydtiyqifnnchcpglrdkpkviivqaarggnsgemwiresskpqlcrgvdlpr
nmead

    Sequence, based on observed residues (ATOM records):
    >6kmuC (C:)
tlklcspeeftrlcrektqeiypikeangrtrkaliicntefkhlslryganfdiigmkg
lledlgydvvvkeeltaegmesemkdfaalsehqtsdstflvlmshgtlhgicgtmhsek
tpdvlqydtiyqifnnchcpglrdkpkviivqaarggnsgemwilprnmead

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6kmuD (D:)
vklshvekdfiafysttphhlsyrdktggsyfitrliscfrkhacschlfdiflkvqqsf
ekasihsqmptidratltryfylfpgn

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6kmuE (E:)
lklcspeeftrlcrektqeiypikeangrtrkaliicntefkhlslryganfdiigmkgl
ledlgydvvvkeeltaegmesemkdfaalsehqtsdstflvlmshgtlhgicgtmhsekt
pdvlqydtiyqifnnchcpglrdkpkviivqaarggnsgemwiresskpqlcrgvdlprn
mead

    Sequence, based on observed residues (ATOM records):
    >6kmuE (E:)
lklcspeeftrlcrektqeiypikeangrtrkaliicntefkhlslryganfdiigmkgl
ledlgydvvvkeeltaegmesemkdfaalsehqtsdstflvlmshgtlhgicgtmhsekt
pdvlqydtiyqifnnchcpglrdkpkviivqaarggnsgemwilprnmead

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6kmuF (F:)
klshvekdfiafysttphhlsyrdktggsyfitrliscfrkhacschlfdiflkvqqsfe
kasihsqmptidratltryfylfpgn

    Sequence, based on observed residues (ATOM records):
    >6kmuF (F:)
hvekdfiafysttphhlsyrdktggsyfitrliscfrkhacschlfdiflkvqqsfekas
ihsqmptidratltryfylfpgn

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >6kmuG (G:)
tlklcspeeftrlcrektqeiypikeangrtrkaliicntefkhlslryganfdiigmkg
lledlgydvvvkeeltaegmesemkdfaalsehqtsdstflvlmshgtlhgicgtmhsek
tpdvlqydtiyqifnnchcpglrdkpkviivqaa

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6kmuH (H:)
klshvekdfiafysttphhlsyrdktggsyfitrliscfrkhacschlfdiflkvqqsfe
kasihsqmptidratltryfylfpgn

    Sequence, based on observed residues (ATOM records):
    >6kmuH (H:)
klshvekdfiafysttphgsyfitrliscfrkhacschlfdiflkvqqsfekasihsqmp
tidratltryfylfpgn