PDB entry 6kgb

View 6kgb on RCSB PDB site
Description: Crystal structure of E61K mutated transthyretin
Class: transport protein
Keywords: T4 transport protein, amyloidogenic protein, TRANSPORT PROTEIN
Deposited on 2019-07-11, released 2020-07-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-09, with a file datestamp of 2020-09-04.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.65 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (92)
    Domains in SCOPe 2.07: d6kgba_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (92)
    Domains in SCOPe 2.07: d6kgbb_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6kgbA (A:)
    mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
    avhvfrkaaddtwepfasgktsesgelhglttkeefvegiykveidtksywkalgispfh
    ehaevvftandsgprrytiaallspysysttavvtnpk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6kgbA (A:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglttkeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6kgbB (B:)
    mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
    avhvfrkaaddtwepfasgktsesgelhglttkeefvegiykveidtksywkalgispfh
    ehaevvftandsgprrytiaallspysysttavvtnpk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6kgbB (B:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglttkeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn