PDB entry 6ke5

View 6ke5 on RCSB PDB site
Description: Structure of CavAb in complex with Diltiazem and Amlodipine
Class: membrane protein
Keywords: Voltage gated Ion Channel, Voltage-gated Calcium Channel, Block, Tetrameric, MEMBRANE PROTEIN
Deposited on 2019-07-03, released 2019-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ion transport protein
    Species: Arcobacter butzleri RM4018 [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5 (17-End)
      • conflict (193-194)
      • conflict (197)
      • conflict (211)
    Domains in SCOPe 2.08: d6ke5a_
  • Chain 'B':
    Compound: Ion transport protein
    Species: Arcobacter butzleri RM4018 [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5 (17-End)
      • conflict (193-194)
      • conflict (197)
      • conflict (211)
    Domains in SCOPe 2.08: d6ke5b_
  • Chain 'C':
    Compound: Ion transport protein
    Species: Arcobacter butzleri RM4018 [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5 (17-End)
      • conflict (193-194)
      • conflict (197)
      • conflict (211)
    Domains in SCOPe 2.08: d6ke5c_
  • Chain 'D':
    Compound: Ion transport protein
    Species: Arcobacter butzleri RM4018 [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5 (17-End)
      • conflict (193-194)
      • conflict (197)
      • conflict (211)
    Domains in SCOPe 2.08: d6ke5d_
  • Heterogens: 6UB, D6C, LPC, G3P, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ke5A (A:)
dykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfgv
yttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrv
lrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgtl
gesfytlfqvmtlddwsngivrplmevypyayvffipfifvvtfvminlvvaiivdamai
lnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records): (download) 
    >6ke5A (A:)
mylritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftiei
ilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrvlrlfrlvtavpqmrkiv
salisvipgmlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtlddws
ngivrplmevypyayvffipfifvvtfvminlvvaiivd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ke5B (B:)
dykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfgv
yttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrv
lrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgtl
gesfytlfqvmtlddwsngivrplmevypyayvffipfifvvtfvminlvvaiivdamai
lnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records): (download) 
    >6ke5B (B:)
mylritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftiei
ilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrvlrlfrlvtavpqmrkiv
salisvipgmlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtlddws
ngivrplmevypyayvffipfifvvtfvminlvvaiivdamailnqkeeqhi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ke5C (C:)
dykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfgv
yttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrv
lrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgtl
gesfytlfqvmtlddwsngivrplmevypyayvffipfifvvtfvminlvvaiivdamai
lnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records): (download) 
    >6ke5C (C:)
mylritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftiei
ilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrvlrlfrlvtavpqmrkiv
salisvipgmlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtlddws
ngivrplmevypyayvffipfifvvtfvminlvvaiivd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6ke5D (D:)
dykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfgv
yttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrv
lrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgtl
gesfytlfqvmtlddwsngivrplmevypyayvffipfifvvtfvminlvvaiivdamai
lnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records): (download) 
    >6ke5D (D:)
mylritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftiei
ilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlrvlrlfrlvtavpqmrkiv
salisvipgmlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtlddws
ngivrplmevypyayvffipfifvvtfvminlvvaiivdamailnqkeeqhi