PDB entry 6kab

View 6kab on RCSB PDB site
Description: Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 2
Class: ligase
Keywords: Inhibitor, Complex, LIGASE
Deposited on 2019-06-21, released 2020-04-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-08, with a file datestamp of 2020-04-03.
Experiment type: XRAY
Resolution: 2.89 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine--tRNA ligase
    Species: Plasmodium falciparum (isolate NF54) [TaxId:5843]
    Gene: PFNF54_04763
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6kaba1, d6kaba2
  • Chain 'B':
    Compound: Lysine--tRNA ligase
    Species: Plasmodium falciparum (isolate NF54) [TaxId:5843]
    Gene: PFNF54_04763
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6kabb1, d6kabb2
  • Chain 'C':
    Compound: Lysine--tRNA ligase
    Species: Plasmodium falciparum (isolate NF54) [TaxId:5843]
    Gene: PFNF54_04763
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6kabc1, d6kabc2
  • Chain 'D':
    Compound: Lysine--tRNA ligase
    Species: Plasmodium falciparum (isolate NF54) [TaxId:5843]
    Gene: PFNF54_04763
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6kabd1, d6kabd2
  • Heterogens: D4U, LYS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6kabA (A:)
mevdprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilni
tgrimrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgf
pgkskkgelsifpketillsaclhmlpmkyglkdteiryrqryldllinessrhtfvtrt
kiinflrnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmli
vggidkvyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgt
ykisynkdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikeh
kielpnpptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemf
icgkevlnaytelndpfkqkecfklqqkdrekgdteaaqldsafctsleyglpptgglgl
gidritmfltnknsikdvilfptmrpangghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6kabA (A:)
vdprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilnitg
rimrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgfpg
kskkgelsifpketillsaclhmlpmkyglkdteiryrqryldllinessrhtfvtrtki
inflrnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmlivg
gidkvyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgtyk
isynkdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikehki
elpnpptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemfic
gkevlnaytelndpfkqkecfklqqkdrekgdteaaqldsafctsleyglpptgglglgi
dritmfltnknsikdvilfptmrpan

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6kabB (B:)
mevdprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilni
tgrimrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgf
pgkskkgelsifpketillsaclhmlpmkyglkdteiryrqryldllinessrhtfvtrt
kiinflrnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmli
vggidkvyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgt
ykisynkdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikeh
kielpnpptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemf
icgkevlnaytelndpfkqkecfklqqkdrekgdteaaqldsafctsleyglpptgglgl
gidritmfltnknsikdvilfptmrpangghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6kabB (B:)
dprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilnitgr
imrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgfpgk
skkgelsifpketillsaclhmlpmkyglkdteiryrqryldllinessrhtfvtrtkii
nflrnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmlivgg
idkvyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgtyki
synkdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikehkie
lpnptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemficgk
evlnaytelndpfkqkecfklqqkdrekgdteaaqldsafctsleyglpptgglglgidr
itmfltnknsikdvilfptmrpa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6kabC (C:)
mevdprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilni
tgrimrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgf
pgkskkgelsifpketillsaclhmlpmkyglkdteiryrqryldllinessrhtfvtrt
kiinflrnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmli
vggidkvyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgt
ykisynkdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikeh
kielpnpptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemf
icgkevlnaytelndpfkqkecfklqqkdrekgdteaaqldsafctsleyglpptgglgl
gidritmfltnknsikdvilfptmrpangghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6kabC (C:)
vdprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilnitg
rimrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgfpg
kskkgelsifpketillsaclhmlpmkyglkdteiryrqryldllinessrhtfvtrtki
inflrnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmlivg
gidkvyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgtyk
isynkdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikehki
elpnpptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemfic
gkevlnaytelndpfkqkecfklqqkdreqldsafctsleyglpptgglglgidritmfl
tnknsikdvilfptmrpa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6kabD (D:)
mevdprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilni
tgrimrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgf
pgkskkgelsifpketillsaclhmlpmkyglkdteiryrqryldllinessrhtfvtrt
kiinflrnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmli
vggidkvyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgt
ykisynkdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikeh
kielpnpptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemf
icgkevlnaytelndpfkqkecfklqqkdrekgdteaaqldsafctsleyglpptgglgl
gidritmfltnknsikdvilfptmrpangghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6kabD (D:)
vdprlyfenrskfiqdqkdkginpyphkfertisipefiekykdlgngehledtilnitg
rimrvsasgqklrffdlvgdgekiqvlanysfhnhekgnfaecydkirrgdivgivgfpg
kskkgelsifpketillsaclhmlpmkyteiryrqryldllinessrhtfvtrtkiinfl
rnflnergffevetpmmnliagganarpfithhndldldlylriatelplkmlivggidk
vyeigkvfrnegidnthnpeftscefywayadyndlikwsedffsqlvyhlfgtykisyn
kdgpenqpieidftppypkvsiveeiekvtntileqpfdsnetiekminiikehkielpn
pptaaklldqlashfienkyndkpffivehpqimsplakyhrtkpglterlemficgkev
lnaytelndpfkqkecfklqqkdrekgdteaaqldsafctsleyglpptgglglgidrit
mfltnknsikdvilfptmrpa