PDB entry 6k9g

View 6k9g on RCSB PDB site
Description: Human LXR-beta in complex with an agonist
Class: DNA binding protein
Keywords: Nuclear receptor, DNA BINDING PROTEIN
Deposited on 2019-06-15, released 2020-04-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-22, with a file datestamp of 2020-04-17.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • engineered mutation (52)
      • engineered mutation (54-55)
      • engineered mutation (57)
      • expression tag (261-270)
    Domains in SCOPe 2.07: d6k9ga1, d6k9ga2
  • Chain 'B':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • engineered mutation (57)
      • expression tag (261-268)
    Domains in SCOPe 2.07: d6k9gb1, d6k9gb2
  • Chain 'C':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • engineered mutation (57)
      • expression tag (262-270)
    Domains in SCOPe 2.07: d6k9gc1, d6k9gc2
  • Chain 'D':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • engineered mutation (57)
      • expression tag (263-269)
    Domains in SCOPe 2.07: d6k9gd1, d6k9gd2
  • Heterogens: D3R, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6k9gA (A:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6k9gA (A:)
ltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqqrfahftelaiisv
qeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskdd
fhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpy
veallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdh
kilhrllqd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6k9gB (B:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6k9gB (B:)
qltaaqelmiqqlvaaqlqcnktpwpsqqrfahftelaiisvqeivdfakqvpgflqlgr
edqiallkastieimlletarrynhetecitflkdftyskddfhraglqvefinpifefs
ramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsytrikrpqdqlr
fprmlmklvslrtlssvhseqvfalrlqdkklppllseiwhkilhrll

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6k9gC (C:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6k9gC (C:)
qltaaqelmiqqlvaaqlqcnsqqrfahftelaiisvqeivdfakqvpgflqlgredqia
llkastieimlletarrynhetecitflkdftyskddfhraglqvefinpifefsramrr
lglddaeyalliainifsadrpnvqepgrvealqqpyveallsytrikrpqdqlrfprml
mklvslrtlssvhseqvfalrlqdkklppllseiwdkilhrllqd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6k9gD (D:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6k9gD (D:)
ltaaqelmiqqlvaaqlqcnkrvtpwplsqqrfahftelaiisvqeivdfakqvpgflql
gredqiallkastieimlletarrynhetecitflkdftyskddfhraglqvefinpife
fsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsytrikrpqdq
lrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdilhrllq