PDB entry 6k7h

View 6k7h on RCSB PDB site
Description: cryo-em structure of the human p4-type flippase atp8a1-cdc50 (e1 state class2)
Deposited on 2019-06-07, released 2019-08-28
The last revision was dated 2021-02-10, with a file datestamp of 2021-02-05.
Experiment type: EM
Resolution: 3.22 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phospholipid-transporting ATPase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Cell cycle control protein 50A
    Species: Homo sapiens [TaxId:9606]
    Gene: CDC50A
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MAN, NAG, Y01

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6k7hA (A:)
gsrefmptmrrtvseirsraegyektddvsektsladqeevrtifinqpqltkfcnnhvs
takyniitflprflysqfrraansfflfiallqqipdvsptgryttlvpllfilavaaik
eiiedikrhkadnavnkkqtqvlrngaweivhwekvnvgdiviikgkeyipadtvllsss
epqamcyietsnldgetnlkirqglpatsdikdvdslmrisgriecespnrhlydfvgni
rldghgtvplgadqillrgaqlrntqwvhgivvytghdtklmqnstspplklsnveritn
vqililfciliamslvcsvgsaiwnrrhsgkdwylnlnyggasnfglnfltfiilfnnli
pisllvtlevvkftqayfinwdldmhyeptdtaamartsnlneelgqvkyifsdktgtlt
cnvmqfkkctiagvaygqnsqfgdektfsdssllenlqnnhptapiicefltmmavchta
vpererdkiiyqaaspdegalvraakqlnfvftgrtpdsviidslgqeeryellnvleft
sarkrmsvivrtpsgklrlyckgadtviydrlaetskykeitlkhleqfateglrtlcfa
vaeisesdfqewravyqrastsvqnrllkleesyelieknlqllgataiedklqdqvpet
ietlmkadikiwiltgdkqetainighsckllkknmgmivinegsldgtretlsrhcttl
gdalrkendfaliidgktlkyaltfgvrqyfldlalsckaviccrvsplqksevvemvkk
qvkvvtlaigdgandvsmiqtahvgvgisgneglqaanssdysiaqfkylknllmihgaw
nynrvskcilycfyknivlyiieiwfafvngfsgqilferwciglynvmftamppltlgi
ferscrkenmlkypelyktsqnaldfntkvfwvhclnglfhsvilfwfplkalqygtafg
ngktsdylllgnfvytfvvitvclkagletsywtwfshiaiwgsialwvvffgiysslwp
aipmapdmsgeaamlfssgvfwmgllfipvasllldvvykvikrtafktlvdevqeleak
sqdpgavvlgkslteraqllknvfkknhvnlyrseslqqnllhgyafsqdengivsqsev
iraydttkqrpdew

    Sequence, based on observed residues (ATOM records):
    >6k7hA (A:)
evrtifinqpqltkfcnnhvstakyniitflprflysqfrraansfflfiallqqipdvs
ptgryttlvpllfilavaaikeiiedikrhkadnavnkkqtqvlrngaweivhwekvnvg
diviikgkeyipadtvllsssepqamcyietsnldgetnlkirqglpatsdikdvdslmr
isgriecespnrhlydfvgnirvplgadqillrgaqlrntqwvhgivvytghdtklmqns
tspplklsnveritnvqililfciliamslvcsvgsaiwnrrhsgkdwylnlnyggasnf
glnfltfiilfnnlipisllvtlevvkftqayfinwdldmhyeptdtaamartsnlneel
gqvkyifsdktgtltcnvmqfkkctiagvaygqnfsdssllenlqnnhptapiicefltm
mavchtavpererdkiiyqaaspdegalvraakqlnfvftgrtpdsviidslgqeeryel
lnvleftsarkrmsvivrtpsgklrlyckgadtviydrlaetskykeitlkhleqfateg
lrtlcfavaeisesdfqewravyqrastsvqnrllkleesyelieknlqllgataiedkl
qdqvpetietlmkadikiwiltgdkqetainighsckllkknmgmivifaliidgktlky
altfgvrqyfldlalsckaviccrvsplqksevvemvkkqvkvvtlaigdgandvsmiqt
ahvgvgisgneglqaanssdysiaqfkylknllmihgawnynrvskcilycfyknivlyi
ieiwfafvngfsgqilferwciglynvmftamppltlgiferscrkenmlkypelyktsq
naldfntkvfwvhclnglfhsvilfwfplkalqygtafgngktsdylllgnfvytfvvit
vclkagletsywtwfshiaiwgsialwvvffgiysslwpaipmapdmsgeaamlfssgvf
wmgllfipvasllldvvykvikrtafk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6k7hC (C:)
mamnynakdevdggppcapggtaktrrpdntafkqqrlpawqpiltagtvlpiffiigli
fipigigifvtsnnireieidytgtepsspcnkclspdvtpcfctinftleksfegnvfm
yyglsnfyqnhrryvksrddsqlngdssallnpskecepyrrnedkpiapcgaiansmfn
dtlelfligndsypipialkkkgiawwtdknvkfrnppggdnleerfkgttkpvnwlkpv
ymldsdpdnngfinedfivwmrtaalptfrklyrlierksdlhptlpagryslnvtynyp
vhyfdgrkrmilstiswmggknpflgiayiavgsisfllgvvllvinhkyrnssntadit
i

    Sequence, based on observed residues (ATOM records):
    >6k7hC (C:)
rpdntafkqqrlpawqpiltagtvlpiffiiglifipigigifvtsnnireieidytgte
psspcnkclspdvtpcfctinftleksfegnvfmyyglsnfyqnhrryvksrddsqlngd
ssallnpskecepyrrnedkpiapcgaiansmfndtlelfligndsypipialkkkgiaw
wtdknvkfrnppggdnleerfkgttkpvnwlkpvymldsdpdnngfinedfivwmrtaal
ptfrklyrlierksdlhptlpagryslnvtynypvhyfdgrkrmilstiswmggknpflg
iayiavgsisfllgvvllvinhkyr