PDB entry 6k0t

View 6k0t on RCSB PDB site
Description: crystal structure of ppargamma ligand binding domain in complex with dibenzooxepine derivative compound-17
Deposited on 2019-05-07, released 2019-10-30
The last revision was dated 2019-11-06, with a file datestamp of 2019-11-01.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6K0T (Start-11)
  • Chain 'C':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6K0T (0-11)
  • Heterogens: CTU, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6k0tA (A:)
gshmaeissdidqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviy
dmnslmmgedkikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnld
lndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfef
avkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessq
lfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records):
    >6k0tA (A:)
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkike
vairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnk
dgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgd
rpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvi
kktetdmslhpllqeiykdly

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6k0tB (B:)
eepsllkkllla

    Sequence, based on observed residues (ATOM records):
    >6k0tB (B:)
psllkkllla

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6k0tC (C:)
gshmaeissdidqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviy
dmnslmmgedkikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnld
lndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfef
avkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessq
lfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records):
    >6k0tC (C:)
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikf
khitpkevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytm
laslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifia
viilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivteh
vqllqvikktetdmslhpllqeiykdly

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6k0tD (D:)
eepsllkkllla