PDB entry 6jpj

View 6jpj on RCSB PDB site
Description: Crystal structure of FGF401 in complex of FGFR4
Class: transferase/transferase inhibitor
Keywords: FGF401, reversible covalent inhibitor, FGFR4, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2019-03-27, released 2019-05-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-05, with a file datestamp of 2019-05-30.
Experiment type: XRAY
Resolution: 2.64 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibroblast growth factor receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR4, JTK2, TKF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22455
      • engineered mutation (34)
      • engineered mutation (221)
    Domains in SCOPe 2.08: d6jpja_
  • Heterogens: FGF, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jpjA (A:)
gpllaglvsldlpldplwefprdrlvlgkplgegafgqvvraeafgmdparpdqastvav
kmlkdnasdkdladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlrefl
rarrppgpdlspdgprssegplsfpvlvscayqvargmqylesrkcihrdlaarnvlvte
dnvmkiadfglargvhhidyykktsngrlpvkwmapealfdevythqsdvwsfgillwei
ftlggspypgipveelfsllreghrmdrpphcppelyglmrecwhaapsqrptfkqlvea
ldkvllavsee

    Sequence, based on observed residues (ATOM records): (download) 
    >6jpjA (A:)
lpldplwefprdrlvlgkplgegafgqvvraeafgmdparpdqastvavkmlkdnasdkd
ladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrppgpdls
pdgprssegplsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfgl
argvhhidyykktsngrlpvkwmapealfdevythqsdvwsfgillweiftlggspypgi
pveelfsllreghrmdrpphcppelyglmrecwhaapsqrptfkqlvealdkvllavse