PDB entry 6jol

View 6jol on RCSB PDB site
Description: Crystal structure of PDGFRA in complex with imatinib by co-crystallization
Class: oncoprotein
Keywords: PDGFRA, Inhibitor, imatinib, ONCOPROTEIN
Deposited on 2019-03-22, released 2020-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-25, with a file datestamp of 2020-03-20.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Platelet-derived growth factor receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PDGFRA, PDGFR2, RHEPDGFRA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jola_
  • Heterogens: STI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jolA (A:)
gamdkqkpryeirwrviesispdgheyiyvdpmqlpydsrwefprdglvlgrvlgsgafg
kvvegtayglsrsqpvmkvavkmlkptarssekqalmselkimthlgphlnivnllgact
ksgpiyiiteycfygdlvnylhknrdsflshkkksmldsevknllsddnsegltlldlls
ftyqvargmeflaskncvhrdlaarnvllaqgkivkicdfglardimhdsnyvskgstfl
pvkwmapesifdnlyttlsdvwsygillweifslggtpypgmmvdstfynkiksgyrmak
pdhatsevyeimvkcwnsepekrpsfyhlseivenllpgqykksyekihldflksd

    Sequence, based on observed residues (ATOM records): (download) 
    >6jolA (A:)
dsrwefprdglvlgrvlgsgafgkvvegtayglsrsqpvmkvavkmlkptarssekqalm
selkimthlgphlnivnllgactksgpiyiiteycfygdlvnylhknrdsfltlldllsf
tyqvargmeflaskncvhrdlaarnvllaqgkivkicdfglardimhdsnyvskgstflp
vkwmapesifdnlyttlsdvwsygillweifslggtpypgmmvdstfynkiksgyrmakp
dhatsevyeimvkcwnsepekrpsfyhlseivenllpgq