PDB entry 6jo8

View 6jo8 on RCSB PDB site
Description: the complex structure of chikv envelope glycoprotein bound to human mxra8
Deposited on 2019-03-20, released 2019-05-15
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-02.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Togavirin
    Species: Chikungunya virus [TaxId:37124]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: chikv e1
    Species: Chikungunya virus [TaxId:37124]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4L787 (20-End)
      • expression tag (18-19)
  • Chain 'C':
    Compound: Togavirin
    Species: Chikungunya virus [TaxId:37124]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: chikv e1
    Species: Chikungunya virus [TaxId:37124]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4L787 (20-End)
      • expression tag (18-19)
  • Chain 'E':
    Compound: Togavirin
    Species: Chikungunya virus [TaxId:37124]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: chikv e1
    Species: Chikungunya virus [TaxId:37124]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4L787 (20-End)
      • expression tag (18-19)
  • Chain 'M':
    Compound: Matrix remodeling-associated protein 8
    Species: Homo sapiens [TaxId:9606]
    Gene: MXRA8
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: Matrix remodeling-associated protein 8
    Species: Homo sapiens [TaxId:9606]
    Gene: MXRA8
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: Matrix remodeling-associated protein 8
    Species: Homo sapiens [TaxId:9606]
    Gene: MXRA8
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6jo8A (A:)
mslaipvmcllanttfpcsqppctpccyekepeetlrmlednvmrpgyyqllqasltcsp
hrqrrstkdnfnvykatrpylahcpdcgeghschspvalerirneatdgtlkiqvslqig
iktddshdwtklrymdnhmpadaeraglfvrtsapctitgtmghfilarcpkgetltvgf
tdsrkishscthpfhhdppvigrekfhsrpqhgkelpcstyvqstaatteeievhmppdt
pdrtlmsqqsgnvkitvngqtvrykcncggsnegltttdkvinnckvdqchaavtnhkkw
qynsplvprnaelgdrkgkihipfplanvtcrvpkarnptvtygknqvimllypdhptll
syrnmgeepnyqeewvmhkkevvltvpteglevtwgnnepykywpq

    Sequence, based on observed residues (ATOM records):
    >6jo8A (A:)
pvmcllanttfpcsqppctpccyekepeetlrmlednvmrpgyyqllqasltcspdnfnv
ykatrpylahcpdcgeghschspvalerirneatdgtlkiqvslqigiktddshdwtklr
ymdnhmpadaeraglfvrtsapctitgtmghfilarcpkgetltvgftdsrkishscthp
fhhdppvigrekfhsrpqhgkelpcstyvqstaatteeievhmppdtpdrtlmsqqsgnv
kitvngqtvrykcncggsnegltttdkvinnckvdqchaavtnhkkwqynsplvprnael
gdrkgkihipfplanvtcrvpkarnptvtygknqvimllypdhptllsyrnmgeepnyqe
ewvmhkkevvltvpteglevtwgnnepykywpq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6jo8B (B:)
ggggsggggsggggsggggsyehvtvipntvgvpyktlvnrpgyspmvlemellsvtlep
tlsldyitceyktvipspyvkccgtaeckdknlpdysckvftgvypfmwggaycfcdaen
tqlseahveksescktefasayrahtasasaklrvlyqgnnitvtayangdhavtvkdak
fivgpmssawtpfdnkivvykgdvynmdyppfgagrpgqfgdiqsrtpeskdvyantqlv
lqrpaagtvhvpysqapsgfkywlkergaslqhtapfgcqiatnpvravncavgnmpisi
dipeaaftrvvdapsltdmscevpacthssdfggvaiikyaaskkgkcavhsmtnavtir
eaeievegnsqlqisfstalasaefrvqvcstqvhcaaechppkdhivnypashttlgvq
disatamswvqk

    Sequence, based on observed residues (ATOM records):
    >6jo8B (B:)
gsyehvtvipntvgvpyktlvnrpgyspmvlemellsvtleptlsldyitceyktvipsp
yvkccgtaeckdknlpdysckvftgvypfmwggaycfcdaentqlseahveksescktef
asayrahtasasaklrvlyqgnnitvtayangdhavtvkdakfivgpmssawtpfdnkiv
vykgdvynmdyppfgagrpgqfgdiqsrtpeskdvyantqlvlqrpaagtvhvpysqaps
gfkywlkergaslqhtapfgcqiatnpvravncavgnmpisidipeaaftrvvdapsltd
mscevpacthssdfggvaiikyaaskkgkcavhsmtnavtireaeievegnsqlqisfst
alasaefrvqvcstqvhcaaechppkdhivnyp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6jo8C (C:)
mslaipvmcllanttfpcsqppctpccyekepeetlrmlednvmrpgyyqllqasltcsp
hrqrrstkdnfnvykatrpylahcpdcgeghschspvalerirneatdgtlkiqvslqig
iktddshdwtklrymdnhmpadaeraglfvrtsapctitgtmghfilarcpkgetltvgf
tdsrkishscthpfhhdppvigrekfhsrpqhgkelpcstyvqstaatteeievhmppdt
pdrtlmsqqsgnvkitvngqtvrykcncggsnegltttdkvinnckvdqchaavtnhkkw
qynsplvprnaelgdrkgkihipfplanvtcrvpkarnptvtygknqvimllypdhptll
syrnmgeepnyqeewvmhkkevvltvpteglevtwgnnepykywpq

    Sequence, based on observed residues (ATOM records):
    >6jo8C (C:)
dnfnvykatrpylahcpdcgeghschspvalerirneatdgtlkiqvslqigiktddshd
wtklrymdnhmpadaeraglfvrtsapctitgtmghfilarcpkgetltvgftdsrkish
scthpfhhdppvigrekfhsrpqhgkelpcstyvqstaatteeievhmppdtpdrtlmsq
qsgnvkitvngqtvrykcncggsnegltttdkvinnckvdqchaavtnhkkwqynsplvp
rnaelgdrkgkihipfplanvtcrvpkarnptvtygknqvimllypdhptllsyrnmgee
pnyqeewvmhkkevvltvpteglevtwgnnepykywpq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6jo8D (D:)
ggggsggggsggggsggggsyehvtvipntvgvpyktlvnrpgyspmvlemellsvtlep
tlsldyitceyktvipspyvkccgtaeckdknlpdysckvftgvypfmwggaycfcdaen
tqlseahveksescktefasayrahtasasaklrvlyqgnnitvtayangdhavtvkdak
fivgpmssawtpfdnkivvykgdvynmdyppfgagrpgqfgdiqsrtpeskdvyantqlv
lqrpaagtvhvpysqapsgfkywlkergaslqhtapfgcqiatnpvravncavgnmpisi
dipeaaftrvvdapsltdmscevpacthssdfggvaiikyaaskkgkcavhsmtnavtir
eaeievegnsqlqisfstalasaefrvqvcstqvhcaaechppkdhivnypashttlgvq
disatamswvqk

    Sequence, based on observed residues (ATOM records):
    >6jo8D (D:)
gsyehvtvipntvgvpyktlvnrpgyspmvlemellsvtleptlsldyitceyktvipsp
yvkccgtaeckdknlpdysckvftgvypfmwggaycfcdaentqlseahveksescktef
asayrahtasasaklrvlyqgnnitvtayangdhavtvkdakfivgpmssawtpfdnkiv
vykgdvynmdyppfgagrpgqfgdiqsrtpeskdvyantqlvlqrpaagtvhvpysqaps
gfkywlkergaslqhtapfgcqiatnpvravncavgnmpisidipeaaftrvvdapsltd
mscevpacthssdfggvaiikyaaskkgkcavhsmtnavtireaeievegnsqlqisfst
alasaefrvqvcstqvhcaaechppkdhivnyp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6jo8E (E:)
mslaipvmcllanttfpcsqppctpccyekepeetlrmlednvmrpgyyqllqasltcsp
hrqrrstkdnfnvykatrpylahcpdcgeghschspvalerirneatdgtlkiqvslqig
iktddshdwtklrymdnhmpadaeraglfvrtsapctitgtmghfilarcpkgetltvgf
tdsrkishscthpfhhdppvigrekfhsrpqhgkelpcstyvqstaatteeievhmppdt
pdrtlmsqqsgnvkitvngqtvrykcncggsnegltttdkvinnckvdqchaavtnhkkw
qynsplvprnaelgdrkgkihipfplanvtcrvpkarnptvtygknqvimllypdhptll
syrnmgeepnyqeewvmhkkevvltvpteglevtwgnnepykywpq

    Sequence, based on observed residues (ATOM records):
    >6jo8E (E:)
dnfnvykatrpylahcpdcgeghschspvalerirneatdgtlkiqvslqigiktddshd
wtklrymdnhmpadaeraglfvrtsapctitgtmghfilarcpkgetltvgftdsrkish
scthpfhhdppvigrekfhsrpqhgkelpcstyvqstaatteeievhmppdtpdrtlmsq
qsgnvkitvngqtvrykcncggsnegltttdkvinnckvdqchaavtnhkkwqynsplvp
rngdrkgkihipfplanvtcrvpkarnptvtygknqvimllypdhptllsyrnmgeepny
qeewvmhkkevvltvpteglevtwgnnepykywpq

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6jo8F (F:)
ggggsggggsggggsggggsyehvtvipntvgvpyktlvnrpgyspmvlemellsvtlep
tlsldyitceyktvipspyvkccgtaeckdknlpdysckvftgvypfmwggaycfcdaen
tqlseahveksescktefasayrahtasasaklrvlyqgnnitvtayangdhavtvkdak
fivgpmssawtpfdnkivvykgdvynmdyppfgagrpgqfgdiqsrtpeskdvyantqlv
lqrpaagtvhvpysqapsgfkywlkergaslqhtapfgcqiatnpvravncavgnmpisi
dipeaaftrvvdapsltdmscevpacthssdfggvaiikyaaskkgkcavhsmtnavtir
eaeievegnsqlqisfstalasaefrvqvcstqvhcaaechppkdhivnypashttlgvq
disatamswvqk

    Sequence, based on observed residues (ATOM records):
    >6jo8F (F:)
gsyehvtvipntvgvpyktlvnrpgyspmvlemellsvtleptlsldyitceyktvipsp
yvkccgtaeckdknlpdysckvftgvypfmwggaycfcdaentqlseahveksescktef
asayrahtasasaklrvlyqgnnitvtayangdhavtvkdakfivgpmssawtpfdnkiv
vykgdvynmdyppfgagrpgqfgdiqsrtpeskdvyantqlvlqrpaagtvhvpysqaps
gfkywlkergaslqhtapfgcqiatnpvravncavgnmpisidipeaaftrvvdapsltd
mscevpacthssdfggvaiikyaaskkgkcavhsmtnavtireaeievegnsqlqisfst
alasaefrvqvcstqvhcaaechppkdhivnyp

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6jo8M (M:)
mgssvpaaagssvvsesavsweagaravlrcqsprmvwtqdrlhdrqrvlhwdlrgpggg
parrlldlysageqrvyeardrgrlelsasafddgnfslliraveetdaglytcnlhhhy
chlyeslavrlevtdgppatpaywdgekevlavargapalltcvnrghvwtdrhveeaqq
vvhwdrqppgvphdradrlldlyasgerraygplflrdrvavgadafergdfslrieple
vadegtyschlhhhycglherrvfhltva

    Sequence, based on observed residues (ATOM records):
    >6jo8M (M:)
gssvvsesavsweagaravlrcqsprmvwtqdrlhdrqrvlhwdlrgpgparrlldlysa
geqrvyeardrgrlelsasafddgnfslliraveetdaglytcnlhhhychlyeslavrl
evtdgppatpaywdgekevlavargapalltcvnrghvwtdrhveeaqqvvhwdrqppgv
phdradrlldlyasgerraygplflrdrvavgadafergdfslrieplevadegtyschl
hhhycglherrvfhltva

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6jo8N (N:)
mgssvpaaagssvvsesavsweagaravlrcqsprmvwtqdrlhdrqrvlhwdlrgpggg
parrlldlysageqrvyeardrgrlelsasafddgnfslliraveetdaglytcnlhhhy
chlyeslavrlevtdgppatpaywdgekevlavargapalltcvnrghvwtdrhveeaqq
vvhwdrqppgvphdradrlldlyasgerraygplflrdrvavgadafergdfslrieple
vadegtyschlhhhycglherrvfhltva

    Sequence, based on observed residues (ATOM records):
    >6jo8N (N:)
gssvvsesavsweagaravlrcqsprmvwtqdrlhdrqrvlhwdlrgpgparrlldlysa
geqrvyeardrgrlelsasafddgnfslliraveetdaglytcnlhhhychlyeslavrl
evtdgppatpaywdgekevlavargapalltcvnrghvwtdrhveeaqqvvhwdrqppgv
phdradrlldlyasgerraygplflrdrvavgadafergdfslrieplevadegtyschl
hhhycglherrvfhltva

  • Chain 'O':
    Sequence, based on SEQRES records:
    >6jo8O (O:)
mgssvpaaagssvvsesavsweagaravlrcqsprmvwtqdrlhdrqrvlhwdlrgpggg
parrlldlysageqrvyeardrgrlelsasafddgnfslliraveetdaglytcnlhhhy
chlyeslavrlevtdgppatpaywdgekevlavargapalltcvnrghvwtdrhveeaqq
vvhwdrqppgvphdradrlldlyasgerraygplflrdrvavgadafergdfslrieple
vadegtyschlhhhycglherrvfhltva

    Sequence, based on observed residues (ATOM records):
    >6jo8O (O:)
gssvvsesavsweagaravlrcqsprmvwtqdrlhdrqrvlhwdlrgpgparrlldlysa
geqrvyeardrgrlelsasafddgnfslliraveetdaglytcnlhhhychlyeslavrl
evtdgppatpaywdgekevlavargapalltcvnrghvwtdrhveeaqqvvhwdrqppgv
phdradrlldlyasgerraygplflrdrvavgadafergdfslrieplevadegtyschl
hhhycglherrvfhltva