PDB entry 6jn5

View 6jn5 on RCSB PDB site
Description: Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor MS23
Class: hydrolase
Keywords: Beta-lactamase, Serine-beta-lactamase KPC-2, KPC-2, Carbapenemase, HYDROLASE
Deposited on 2019-03-13, released 2019-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-21, with a file datestamp of 2019-08-16.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine Beta-Lactamase KPC-2
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: KPC-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jn5a_
  • Chain 'B':
    Compound: Serine Beta-Lactamase KPC-2
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: KPC-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jn5b_
  • Chain 'C':
    Compound: Serine Beta-Lactamase KPC-2
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: KPC-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jn5c_
  • Chain 'D':
    Compound: Serine Beta-Lactamase KPC-2
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: KPC-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jn5d_
  • Heterogens: BXU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6jn5A (A:)
tnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqq
qaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpa
gltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqq
fvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytra
pnkddkhseaviaaaarlaleglg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jn5B (B:)
tnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqq
qaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpa
gltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqq
fvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytra
pnkddkhseaviaaaarlaleglg

    Sequence, based on observed residues (ATOM records): (download) 
    >6jn5B (B:)
vaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqqqag
lldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpaglt
afmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqqfvd
wlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytrapnk
ddkhseaviaaaarlaleglg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6jn5C (C:)
tnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqq
qaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpa
gltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqq
fvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytra
pnkddkhseaviaaaarlaleglg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6jn5D (D:)
tnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqq
qaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpa
gltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqq
fvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytra
pnkddkhseaviaaaarlaleglg

    Sequence, based on observed residues (ATOM records): (download) 
    >6jn5D (D:)
aepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqqqagl
ldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpaglta
fmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqqfvdw
lkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytrapnkd
dkhseaviaaaarlaleglg