PDB entry 6jn2

View 6jn2 on RCSB PDB site
Description: crystal structure of the coiled-coil domains of human dot1l in complex with af10
Deposited on 2019-03-13, released 2019-09-18
The last revision was dated 2019-10-16, with a file datestamp of 2019-10-11.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein AF-10
    Species: Homo sapiens [TaxId:9606]
    Gene: MLLT10, AF10
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase, H3 lysine-79 specific
    Species: Homo sapiens [TaxId:9606]
    Gene: DOT1L, KIAA1814, KMT4
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6jn2A (A:)
    mgsshhhhhhsqdpdqpgnsslenlppvaasieqllerqwsegqqflleqgtpsdilgml
    kslhqlqvenrrleeqiknltakkerlqllnaqlsvpf
    

    Sequence, based on observed residues (ATOM records):
    >6jn2A (A:)
    sieqllerqwsegqqflleqgtpsdilgmlkslhqlqvenrrleeqiknltakkerlqll
    naqlsvp
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6jn2B (B:)
    mhspnpllvaptppalqkllesfkiqylqflaytktpqykaslqellgqekeknaqllga
    aqqllshcqaqkeeirrlfqqk
    

    Sequence, based on observed residues (ATOM records):
    >6jn2B (B:)
    alqkllesfkiqylqflaytktpqykaslqellgqekeknaqllgaaqqllshcqaqkee
    irrlfqq