PDB entry 6jm4

View 6jm4 on RCSB PDB site
Description: the crystal structure of pb1 homo-dimer of human p62/sqstm1
Deposited on 2019-03-07, released 2020-01-15
The last revision was dated 2020-01-15, with a file datestamp of 2020-01-10.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sequestosome-1
    Species: Homo sapiens [TaxId:9606]
    Gene: SQSTM1, ORCA, OSIL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13501 (Start-101)
      • engineered mutation (25)
      • engineered mutation (68)
      • engineered mutation (70)
  • Chain 'B':
    Compound: Sequestosome-1
    Species: Homo sapiens [TaxId:9606]
    Gene: SQSTM1, ORCA, OSIL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13501
      • engineered mutation (20)
      • engineered mutation (25-26)
  • Chain 'C':
    Compound: Sequestosome-1
    Species: Homo sapiens [TaxId:9606]
    Gene: SQSTM1, ORCA, OSIL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13501 (Start-101)
      • engineered mutation (25-26)
      • engineered mutation (68)
      • engineered mutation (70)
  • Chain 'D':
    Compound: Sequestosome-1
    Species: Homo sapiens [TaxId:9606]
    Gene: SQSTM1, ORCA, OSIL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13501 (Start-101)
      • engineered mutation (20)
      • engineered mutation (25-26)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6jm4A (A:)
masltvkayllgkedaareirrfsfsfspepeaeaeaaagpgpcerllsrvaalfpalrp
ggfqahyraergdlvafssdeeltmamsyvkddifriyikek

    Sequence, based on observed residues (ATOM records):
    >6jm4A (A:)
ltvkayllgkdaareirrfsfspgpcerllsrvaalfpalrpggfqahyraergdlvafs
sdeeltmamsydifriyikek

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6jm4B (B:)
masltvkayllgkedaareiarfsfsfspepeaeaeaaagpgpcerllsrvaalfpalrp
ggfqahyrdedgdlvafssdeeltmamsyvkddifriyikek

    Sequence, based on observed residues (ATOM records):
    >6jm4B (B:)
ltvkaylliarfsfsfgpcerllsrvaalfparpggfqahyrdedgdlvafssdeeltma
msyvkddifriyike

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6jm4C (C:)
masltvkayllgkedaareirrfsfsfspepeaeaeaaagpgpcerllsrvaalfpalrp
ggfqahyraergdlvafssdeeltmamsyvkddifriyikek

    Sequence, based on observed residues (ATOM records):
    >6jm4C (C:)
sltvkayllgaareirrfsfsfspgpcerllsrvaalfpalrpggfqahyraergdlvaf
ssdeeltmamsydifriyikek

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6jm4D (D:)
masltvkayllgkedaareiarfsfsfspepeaeaeaaagpgpcerllsrvaalfpalrp
ggfqahyrdedgdlvafssdeeltmamsyvkddifriyikek

    Sequence, based on observed residues (ATOM records):
    >6jm4D (D:)
ltvkaylldaareiarfsfsfspgpcerllsrvaalfpalrpggfqahyrdedgdlvafs
sdeeltmamsyvkddifriyikek