PDB entry 6jlz

View 6jlz on RCSB PDB site
Description: p-eif2a - eif2b complex
Deposited on 2019-03-07, released 2019-05-01
The last revision was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 3.35 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Translation initiation factor eIF-2B subunit alpha
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif221, SPCC11E10.07c
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Translation initiation factor eIF-2B subunit alpha
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif221, SPCC11E10.07c
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Probable translation initiation factor eIF-2B subunit beta
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif222, SPAC343.14c
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UT76 (6-398)
      • expression tag (0-5)
  • Chain 'D':
    Compound: Probable translation initiation factor eIF-2B subunit beta
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif222, SPAC343.14c
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UT76 (6-398)
      • expression tag (0-5)
  • Chain 'E':
    Compound: Probable translation initiation factor eIF-2B subunit gamma
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif223, SPAC4D7.09
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56288
      • conflict (156-158)
  • Chain 'F':
    Compound: Probable translation initiation factor eIF-2B subunit gamma
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif223, SPAC4D7.09
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56288
      • conflict (156-158)
  • Chain 'G':
    Compound: Probable translation initiation factor eIF-2B subunit delta
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif224, SPAC21E11.06
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Probable translation initiation factor eIF-2B subunit delta
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif224, SPAC21E11.06
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Probable translation initiation factor eIF-2B subunit epsilon
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif225, SPAC8C9.15c
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Probable translation initiation factor eIF-2B subunit epsilon
    Species: Schizosaccharomyces pombe (strain 972 / ATCC 24843) [TaxId:284812]
    Gene: tif225, SPAC8C9.15c
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Eukaryotic translation initiation factor 2 subunit alpha
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: SUI2, TIF211, YJR007W, J1429
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: Eukaryotic translation initiation factor 2 subunit alpha
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: SUI2, TIF211, YJR007W, J1429
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PO4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6jlzA (A:)
mvesdssgivrhsqgefdivqvykkflqddpeitmpvaaiealvqllsrsqaktisefmd
ilqngsntlkegvqnnislsagcdifqrfvtrslhdvgdfeqckrhlvengklfiqrara
crqriahlgyplirdgsvilthgfsrgvaavllaaakrhvrfkvfvtesrpsgsgclmtr
tlknaciptcmvldsavsftmnrvdlvlvgaegvvengglinqigtfqlavfakhahkpf
yavaeshkfvrmfplsqydipfsrpilefddpspetvhpepepiptpsdaihnelimnee
qirnnptldvtppefvsglitdlgiidsksgvseeliklyl

    Sequence, based on observed residues (ATOM records):
    >6jlzA (A:)
qgefdivqvykkflqddpeitmpvaaiealvqllsrsqaktisefmdilqngsntlkegv
qnnislsagcdifqrfvtrslhdvgdfeqckrhlvengklfiqraracrqriahlgypli
rdgsvilthgfsrgvaavllaaakrhvrfkvfvtesrpsgsgclmtrtlknaciptcmvl
dsavsftmnrvdlvlvgaegvvengglinqigtfqlavfakhahkpfyavaeshkfvrmf
plsqydipfsrpilefddpspetvhaihnelimneeqirnnptldvtppefvsglitdlg
iidsksgvseeliklyl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6jlzB (B:)
mvesdssgivrhsqgefdivqvykkflqddpeitmpvaaiealvqllsrsqaktisefmd
ilqngsntlkegvqnnislsagcdifqrfvtrslhdvgdfeqckrhlvengklfiqrara
crqriahlgyplirdgsvilthgfsrgvaavllaaakrhvrfkvfvtesrpsgsgclmtr
tlknaciptcmvldsavsftmnrvdlvlvgaegvvengglinqigtfqlavfakhahkpf
yavaeshkfvrmfplsqydipfsrpilefddpspetvhpepepiptpsdaihnelimnee
qirnnptldvtppefvsglitdlgiidsksgvseeliklyl

    Sequence, based on observed residues (ATOM records):
    >6jlzB (B:)
gefdivqvykkflqddpeitmpvaaiealvqllsrsqaktisefmdilqngsntlkegvq
nnislsagcdifqrfvtrslhdvgdfeqckrhlvengklfiqraracrqriahlgyplir
dgsvilthgfsrgvaavllaaakrhvrfkvfvtesrpsgsgclmtrtlknaciptcmvld
savsftmnrvdlvlvgaegvvengglinqigtfqlavfakhahkpfyavaeshkfvrmfp
lsqydipfsrpilefddpspetvaihnelimneeqirnnptldvtppefvsglitdlgii
dsksgvseeliklyl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6jlzC (C:)
gpisefmstinvehtypavssliadlksrkvqgpfavavetalvmrqvisqtrwstvdql
idtvravgstlvkaqptefscgniirrilrlireeyqellktadeneklivsssnsssps
qkrdipsneklvqshepvsvqmyssmlnllgrptlespthsktvgdsrvtggmdmravii
sgiqdvideldkintdievqsmdhlhsneiiltqgcsktveaflrfaakkrkfsvivaeg
fpnnqkgshamakrlaqagidttvisdatifaimsrvnkvilgthailgngglvtysgaq
lvaqaarhhatpvvvcsgiyklspvypydlesiiqlsspdkimsfnegdlisraeilnpy
ydyippdlvdlfitnlggyppsylyrimndtydasdtil

    Sequence, based on observed residues (ATOM records):
    >6jlzC (C:)
gpisefmstinvehtypavssliadlksrkvqgpfavavetalvmrqvisqtrwstvdql
idtvravgstlvkaqptefscgniirrilrlireeyqellktadenekggmdmraviisg
iqdvideldkintdievqsmdhlhsneiiltqgcsktveaflrfaakkrkfsvivaegfp
nnqkgshamakrlaqagidttvisdatifaimsrvnkvilgthailgngglvtysgaqlv
aqaarhhatpvvvcsgiyklspvypydlesiiqlsspdkimsfnegdlisraeilnpyyd
yippdlvdlfitnlggyppsylyrimndtydasdtil

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6jlzD (D:)
gpisefmstinvehtypavssliadlksrkvqgpfavavetalvmrqvisqtrwstvdql
idtvravgstlvkaqptefscgniirrilrlireeyqellktadeneklivsssnsssps
qkrdipsneklvqshepvsvqmyssmlnllgrptlespthsktvgdsrvtggmdmravii
sgiqdvideldkintdievqsmdhlhsneiiltqgcsktveaflrfaakkrkfsvivaeg
fpnnqkgshamakrlaqagidttvisdatifaimsrvnkvilgthailgngglvtysgaq
lvaqaarhhatpvvvcsgiyklspvypydlesiiqlsspdkimsfnegdlisraeilnpy
ydyippdlvdlfitnlggyppsylyrimndtydasdtil

    Sequence, based on observed residues (ATOM records):
    >6jlzD (D:)
gpisefmstinvehtypavssliadlksrkvqgpfavavetalvmrqvisqtrwstvdql
idtvravgstlvkaqptefscgniirrilrlireeyqellktadenekggmdmraviisg
iqdvideldkintdievqsmdhlhsneiiltqgcsktveaflrfaakkrkfsvivaegfp
nnqkgshamakrlaqagidttvisdatifaimsrvnkvilgthailgngglvtysgaqlv
aqaarhhatpvvvcsgiyklspvypydlesiiqlsspdkimsfnegdlisraeilnpyyd
yippdlvdlfitnlggyppsylyrimndtydasdtil

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6jlzE (E:)
mslyehaalplasspsilgpisggrnrgniqlqsipiefqavvfagfgnslypltgsdal
pkallpignkpmlhyplywleaagftsailicmeeaeahinawlrsgyeghmrihveapt
ilddskssadalravshlikndfvclscdsivglppytvldkfrldnpsalavyspvlky
ehitsqskeidakqligieektsrllyakssadvgsdftfrmsllwkhprvtlntnlsda
hifvfkhwvidlirekesissirgdlipylvkcqyqksftvreniqrflsspnnidnydg
glssqeikinaliakdgiicsrannlpnyfelnkciakltpeqrlvdvtvseralvgadc
mvnegttikdnsnikksiigkncvigkgvvvsnsilmdnivvedgvrlescivasgaqig
aksklreceigvdhrveagriargerlvdmekietdmd

    Sequence, based on observed residues (ATOM records):
    >6jlzE (E:)
lqsipiefqavvfagfgnslypltgsdalpkallpignkpmlhyplywleaagftsaili
cmeeaeahinawlrsgyeghmrihveaptilddskssadalravshlikndfvclscdsi
vglppytvldkfrldnpsalavyspvlkyehitsqskeidakqligieektsrllyakss
advgsdftfrmsllwkhprvtlntnlsdahifvfkhwvidlirekesissirgdlipylv
kcqyqksftvreniqrflsspssqeikinaliakdgiicsrannlpnyfelnkciakltp
eqrlvdvtvseralvgadcmvnegttikdnsnikksiigkncvigkgvvvsnsilmdniv
vedgvrlescivasgaqigaksklreceigvdhrveagriargerlvdm

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6jlzF (F:)
mslyehaalplasspsilgpisggrnrgniqlqsipiefqavvfagfgnslypltgsdal
pkallpignkpmlhyplywleaagftsailicmeeaeahinawlrsgyeghmrihveapt
ilddskssadalravshlikndfvclscdsivglppytvldkfrldnpsalavyspvlky
ehitsqskeidakqligieektsrllyakssadvgsdftfrmsllwkhprvtlntnlsda
hifvfkhwvidlirekesissirgdlipylvkcqyqksftvreniqrflsspnnidnydg
glssqeikinaliakdgiicsrannlpnyfelnkciakltpeqrlvdvtvseralvgadc
mvnegttikdnsnikksiigkncvigkgvvvsnsilmdnivvedgvrlescivasgaqig
aksklreceigvdhrveagriargerlvdmekietdmd

    Sequence, based on observed residues (ATOM records):
    >6jlzF (F:)
lqsipiefqavvfagfgnslypltgsdalpkallpignkpmlhyplywleaagftsaili
cmeeaeahinawlrsgyeghmrihveaptilddskssadalravshlikndfvclscdsi
vglppytvldkfrldnpsalavyspvlkyehitsqskeidakqligieektsrllyakss
advgsdftfrmsllwkhprvtlntnlsdahifvfkhwvidlirekesissirgdlipylv
kcqyqksftvreniqrflsspssqeikinaliakdgiicsrannlpnyfelnkciakltp
eqrlvdvtvseralvgadcmvnegttikdnsnikksiigkncvigkgvvvsnsilmdniv
vedgvrlescivasgaqigaksklreceigvdhrveagriargerlvdm

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6jlzG (G:)
mgfsaeqakkdgkdqspvsesssvggtspatassvvspnepklsgkeakalkkarkqasr
rakaeaaaannppgvseekkvaipnknsnqqkkaskqnpqnspetdanlqekkifeekqv
sifshldwrrrrttenipkdihpavirlglklanykifgsnqrcidllktfkiviqdyqt
pygttlsrhltthinsqiaylvstrplsismgnairflkleisvldidltddegkellle
kidsyirdriiiagqvivqaatekiqdgdviltylhsstvndvlihaknvgkkfrvvvvd
srpefegrvclklltehgiectyvmisalsyimqevtkiflgghamlsngalysragtsl
isllghesnvpviaccesykfteriqldslvynelapgdqlvnmgvddfeekpgvlanwk
svknlkllslkydvtpprlitvcvcemgllpstsvpaiinefkqvya

    Sequence, based on observed residues (ATOM records):
    >6jlzG (G:)
danlqekkifeekqvsifshldwrrrrttenipkdihpavirlglklanykifgsnqrci
dllktfkiviqdyqtpygttlsrhltthinsqiaylvstrplsismgnairflkleisvl
didltddegkelllekidsyirdriiiagqvivqaatekiqdgdviltylhsstvndvli
haknvgkkfrvvvvdsrpefegrvclklltehgiectyvmisalsyimqevtkiflggha
mlsngalysragtslisllghesnvpviaccesykfteriqldslvynelapgdqlvnmg
vddfeekpgvlanwksvknlkllslkydvtpprlitvcvcemgllpstsvpaiinefkqv

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6jlzH (H:)
mgfsaeqakkdgkdqspvsesssvggtspatassvvspnepklsgkeakalkkarkqasr
rakaeaaaannppgvseekkvaipnknsnqqkkaskqnpqnspetdanlqekkifeekqv
sifshldwrrrrttenipkdihpavirlglklanykifgsnqrcidllktfkiviqdyqt
pygttlsrhltthinsqiaylvstrplsismgnairflkleisvldidltddegkellle
kidsyirdriiiagqvivqaatekiqdgdviltylhsstvndvlihaknvgkkfrvvvvd
srpefegrvclklltehgiectyvmisalsyimqevtkiflgghamlsngalysragtsl
isllghesnvpviaccesykfteriqldslvynelapgdqlvnmgvddfeekpgvlanwk
svknlkllslkydvtpprlitvcvcemgllpstsvpaiinefkqvya

    Sequence, based on observed residues (ATOM records):
    >6jlzH (H:)
danlqekkifeekqvsifshldwrrrrttenipkdihpavirlglklanykifgsnqrci
dllktfkiviqdyqtpygttlsrhltthinsqiaylvstrplsismgnairflkleisvl
didltddegkelllekidsyirdriiiagqvivqaatekiqdgdviltylhsstvndvli
haknvgkkfrvvvvdsrpefegrvclklltehgiectyvmisalsyimqevtkiflggha
mlsngalysragtslisllghesnvpviaccesykfteriqldslvynelapgdqlvnmg
vddfeekpgvlanwksvknlkllslkydvtpprlitvcvcemgllpstsvpaiinefkqv
y

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6jlzI (I:)
mppskglngklekpkhalqaivlsdsynyrfrpltldkprcllplantplieytfeflal
agvqevyvfccahagqireyiekskwnlpsspfsvntivsreslsvgdalreldskqlit
sdfilvsgdvvsnvplnevlkehrkrreddknaimtmvvreaspfhrtrartessvfvid
kktsqcvhyqanergkhyvsmdpeifneheelevrndlidcqidicsndvpalftenfdy
qdirkdfvygvltsdllgkkihchvakenyaarvrslqtydaiskdvlsrwvypfvpdsn
llnqtfsyqrhqiykeedvvlarsciikartligaytkvgdasvvantiigrnctigsnc
sidsaflwedvvigdncrigkailansvkignncsiedgaivaagvvigdntiieknkrl
ttfeshsqgtlndpslvgiggrgqeyhaeedsddegefmeasgliestnelhlsdsesse
tsssseedmefipfsarrdsantinsedfdegdfnkeaqqslerafeenhqidiaaleln
tlrmamnanyhevrsaivlallrrimhldvspkealakvmtrwgpllakltfsheeqvdn
vltlqkycvrlsmtrhflqllgyfyqleiaeenaiqewysdprssegelaalrdaggkqf
vdwlntaeseseseegse

    Sequence, based on observed residues (ATOM records):
    >6jlzI (I:)
kpkhalqaivlsdsynyrfrpltldkprcllplantplieytfeflalagvqevyvfcca
hagqireyiekskwnlpsspfsvntivsreslsvgdalreldskqlitsdfilvsgdvvs
nvplnevlkehrkrreddknaimtmvvreaspfhrtrartessvfvidkktsqcvhyqan
ergkhyvsmdpeifneheelevrndlidcqidicsndvpalftenfdyqdirkdfvygvl
tsdllgkkihchvakenyaarvrslqtydaiskdvlsrwvypfvpdsnllnqtfsyqrhq
iykeedvvlarsciikartligaytkvgdasvvantiigrnctigsncsidsaflwedvv
igdncrigkailansvkignncsiedgaivaagvvigdntiieknkrlttfeshsqgtln
dpslvgiggr

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6jlzJ (J:)
mppskglngklekpkhalqaivlsdsynyrfrpltldkprcllplantplieytfeflal
agvqevyvfccahagqireyiekskwnlpsspfsvntivsreslsvgdalreldskqlit
sdfilvsgdvvsnvplnevlkehrkrreddknaimtmvvreaspfhrtrartessvfvid
kktsqcvhyqanergkhyvsmdpeifneheelevrndlidcqidicsndvpalftenfdy
qdirkdfvygvltsdllgkkihchvakenyaarvrslqtydaiskdvlsrwvypfvpdsn
llnqtfsyqrhqiykeedvvlarsciikartligaytkvgdasvvantiigrnctigsnc
sidsaflwedvvigdncrigkailansvkignncsiedgaivaagvvigdntiieknkrl
ttfeshsqgtlndpslvgiggrgqeyhaeedsddegefmeasgliestnelhlsdsesse
tsssseedmefipfsarrdsantinsedfdegdfnkeaqqslerafeenhqidiaaleln
tlrmamnanyhevrsaivlallrrimhldvspkealakvmtrwgpllakltfsheeqvdn
vltlqkycvrlsmtrhflqllgyfyqleiaeenaiqewysdprssegelaalrdaggkqf
vdwlntaeseseseegse

    Sequence, based on observed residues (ATOM records):
    >6jlzJ (J:)
khalqaivlsdsynyrfrpltldkprcllplantplieytfeflalagvqevyvfccaha
gqireyiekskwnlpsspfsvntivsreslsvgdalreldskqlitsdfilvsgdvvsnv
plnevlkehrkrreddknaimtmvvreaspfhrtrartessvfvidkktsqcvhyqaner
gkhyvsmdpeifneheelevrndlidcqidicsndvpalftenfdyqdirkdfvygvlts
dllgkkihchvakenyaarvrslqtydaiskdvlsrwvypfvpdsnllnqtfsyqrhqiy
keedvvlarsciikartligaytkvgdasvvantiigrnctigsncsidsaflwedvvig
dncrigkailansvkignncsiedgaivaagvvigdntiieknkrlttfeshsqgtlndp
slvgiggr

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6jlzL (L:)
mstshcrfyenkypeiddivmvnvqqiaemgayvklleydniegmillselsrrrirsiq
klirvgkndvavvlrvdkekgyidlskrrvssediikceekyqksktvhsilrycaekfq
ipleelyktiawplsrkfghayeafklsiidetvwegieppskdvldelknyiskrltpq
avkiradvevscfsyegidaikdalksaedmsteqmqvkvklvaaplyvlttqaldkqkg
ieqlesaiekitevitkyggvcnitmppkavtatedaelqalleskeldnrsdseddede
sdde

    Sequence, based on observed residues (ATOM records):
    >6jlzL (L:)
hcrfyenkypeiddivmvnvqqiaemgayvklleydniegmillselsrrrirsiqklir
vgkndvavvlrvdkekgyidlskrrvssediikceekyqksktvhsilrycaeleelykt
iawplsrkfghayeafklsiidetvwegieppskdvldelknyiskr

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6jlzM (M:)
mstshcrfyenkypeiddivmvnvqqiaemgayvklleydniegmillselsrrrirsiq
klirvgkndvavvlrvdkekgyidlskrrvssediikceekyqksktvhsilrycaekfq
ipleelyktiawplsrkfghayeafklsiidetvwegieppskdvldelknyiskrltpq
avkiradvevscfsyegidaikdalksaedmsteqmqvkvklvaaplyvlttqaldkqkg
ieqlesaiekitevitkyggvcnitmppkavtatedaelqalleskeldnrsdseddede
sdde

    Sequence, based on observed residues (ATOM records):
    >6jlzM (M:)
tshcrfyenkypeiddivmvnvqqiaemgayvklleydniegmillselsrrrirsiqkl
irvgkndvavvlrvdkekgyidlskrrvssediikceekyqksktvhsilrycaeleely
ktiawplsrkfghayeafklsiidetvwegieppskdvldelknyiskr