PDB entry 6jlr

View 6jlr on RCSB PDB site
Description: Crystal structure of wild type MNK2 in complex with inhibitor
Class: transferase/transferase inhibitor
Keywords: Kinase, phosphorylation, inhibitor, MNK, kinase domain, TRANSFERASE, cancer, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2019-03-06, released 2020-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MAP kinase-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MKNK2, GPRK7, MNK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HBH9 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d6jlra1, d6jlra2
  • Heterogens: BV9

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jlrA (A:)
gstdsfsgrfedvyqlqedvlgegaharvqtcinlitsqeyavkiiekqpghirsrvfre
vemlyqcqghrnvlelieffeeedrfylvfekmrggsilshihkrrhfneleasvvvqdv
asaldflhnkgiahrdlkpenilcehpnqvspvkicdfdlgsgiklngdcspistpellt
pcgsaeymapevveafseeasiydkrcdlwslgvilyillsgyppfvgrcgsdcgwdrge
acpacqnmlfesiqegkyefpdkdwahiscaakdliskllvrdakqrlsaaqvlqhpwvq
gcapentlptpmvlqr

    Sequence, based on observed residues (ATOM records): (download) 
    >6jlrA (A:)
stdsfsgrfedvyqlqedvlgegaharvqtcinlitsqeyavkiiekqpghirsrvfrev
emlyqcqghrnvlelieffeeedrfylvfekmrggsilshihkrrhfneleasvvvqdva
saldflhnkgiahrdlkpenilcehpnqvspvkicdfdlgsgsaeymapevveafseeas
iydkrcdlwslgvilyillsgyppfvgrcgpacqnmlfesiqegkyefpdkdwahiscaa
kdliskllvrdakqrlsaaqvlqhpwvq