PDB entry 6jlr
View 6jlr on RCSB PDB site
Description: Crystal structure of wild type MNK2 in complex with inhibitor
Class: transferase/transferase inhibitor
Keywords: Kinase, phosphorylation, inhibitor, MNK, kinase domain, TRANSFERASE, cancer, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2019-03-06, released
2020-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-02-12, with a file datestamp of
2020-02-07.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: MAP kinase-interacting serine/threonine-protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: MKNK2, GPRK7, MNK2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6jlra1, d6jlra2 - Heterogens: BV9
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6jlrA (A:)
gstdsfsgrfedvyqlqedvlgegaharvqtcinlitsqeyavkiiekqpghirsrvfre
vemlyqcqghrnvlelieffeeedrfylvfekmrggsilshihkrrhfneleasvvvqdv
asaldflhnkgiahrdlkpenilcehpnqvspvkicdfdlgsgiklngdcspistpellt
pcgsaeymapevveafseeasiydkrcdlwslgvilyillsgyppfvgrcgsdcgwdrge
acpacqnmlfesiqegkyefpdkdwahiscaakdliskllvrdakqrlsaaqvlqhpwvq
gcapentlptpmvlqr
Sequence, based on observed residues (ATOM records): (download)
>6jlrA (A:)
stdsfsgrfedvyqlqedvlgegaharvqtcinlitsqeyavkiiekqpghirsrvfrev
emlyqcqghrnvlelieffeeedrfylvfekmrggsilshihkrrhfneleasvvvqdva
saldflhnkgiahrdlkpenilcehpnqvspvkicdfdlgsgsaeymapevveafseeas
iydkrcdlwslgvilyillsgyppfvgrcgpacqnmlfesiqegkyefpdkdwahiscaa
kdliskllvrdakqrlsaaqvlqhpwvq