PDB entry 6jlf

View 6jlf on RCSB PDB site
Description: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae D179A mutation - HR
Class: membrane protein
Keywords: Bestrophin-1, homolog, mutation, klebsiella pneumoniae, MEMBRANE PROTEIN
Deposited on 2019-03-05, released 2019-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6jlfa_
  • Chain 'B':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6jlfb_
  • Chain 'C':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6jlfc_
  • Chain 'D':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6jlfd_
  • Chain 'E':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6jlfe_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6jlfA (A:)
    snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
    sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
    lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkl
    saityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
    tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe
    

    Sequence, based on observed residues (ATOM records): (download)
    >6jlfA (A:)
    skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
    arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
    lpeervteilassmptnrilllagneigqlreagklsaityglmdnkldelahvlggcer
    lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
    pfgtaandlplnamcntiernlldmtg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6jlfB (B:)
    snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
    sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
    lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkl
    saityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
    tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe
    

    Sequence, based on observed residues (ATOM records): (download)
    >6jlfB (B:)
    kiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvea
    rnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrll
    peervteilassmptnrilllagneigqlreagklsaityglmdnkldelahvlggcerl
    attpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledp
    fgtaandlplnamcntiernlldmtg
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6jlfC (C:)
    snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
    sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
    lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkl
    saityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
    tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe
    

    Sequence, based on observed residues (ATOM records): (download)
    >6jlfC (C:)
    kiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvea
    rnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrll
    peervteilassmptnrilllagneigqlreagklsaityglmdnkldelahvlggcerl
    attpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledp
    fgtaandlplnamcntiernlldmtgqh
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6jlfD (D:)
    snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
    sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
    lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkl
    saityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
    tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe
    

    Sequence, based on observed residues (ATOM records): (download)
    >6jlfD (D:)
    skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
    arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
    lpeervteilassmptnrilllagneigqlreagklsaityglmdnkldelahvlggcer
    lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
    pfgtaandlplnamcntiernlldmtgq
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >6jlfE (E:)
    snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
    sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
    lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkl
    saityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
    tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe
    

    Sequence, based on observed residues (ATOM records): (download)
    >6jlfE (E:)
    iifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvear
    nlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrllp
    eervteilassmptnrilllagneigqlreagklsaityglmdnkldelahvlggcerla
    ttpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledpf
    gtaandlplnamcntiernlldmtgq