PDB entry 6jks

View 6jks on RCSB PDB site
Description: Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with carbamoyl phosphate (CP) and aspartate (Asp)
Class: transferase
Keywords: ATCase, Pyrimidine metabolism, TRANSFERASE
Deposited on 2019-03-01, released 2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aspartate carbamoyltransferase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053508375.30
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jksa1, d6jksa2
  • Chain 'B':
    Compound: Aspartate carbamoyltransferase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053508375.30
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W3 (2-327)
      • expression tag (1)
    Domains in SCOPe 2.08: d6jksb1, d6jksb2, d6jksb3
  • Chain 'C':
    Compound: Aspartate carbamoyltransferase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053508375.30
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W3 (2-327)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6jksc1, d6jksc2, d6jksc3
  • Chain 'D':
    Compound: Aspartate carbamoyltransferase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053508375.30
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W3 (2-327)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6jksd1, d6jksd2, d6jksd3
  • Chain 'E':
    Compound: Aspartate carbamoyltransferase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053508375.30
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jkse1, d6jkse2
  • Chain 'F':
    Compound: Aspartate carbamoyltransferase, putative
    Species: Trypanosoma cruzi (strain CL Brener) [TaxId:353153]
    Gene: Tc00.1047053508375.30
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4D3W3 (2-327)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6jksf1, d6jksf2, d6jksf3
  • Heterogens: CP, ASP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jksA (A:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jksA (A:)
elppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffeds
srtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqdaiee
alsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkl
lvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttr
lqkerftsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpraa
yfrqmrygmfmrmailwsvla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jksB (B:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jksB (B:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmai
lwsvla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6jksC (C:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jksC (C:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmai
lwsvla

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6jksD (D:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6jksE (E:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jksE (E:)
elppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffeds
srtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqdaiee
alsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkl
lvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttr
lqditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailwsv
la

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6jksF (F:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jksF (F:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqdaaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpraayfr
qmrygmfmrmailwsvla