PDB entry 6jkr

View 6jkr on RCSB PDB site
Description: Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with carbamoyl phosphate (CP)
Class: transferase
Keywords: ATCase, Pyrimidine metabolism, TRANSFERASE
Deposited on 2019-03-01, released 2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (2-327)
      • expression tag (1)
    Domains in SCOPe 2.08: d6jkra1, d6jkra2, d6jkra3
  • Chain 'B':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (2-327)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6jkrb1, d6jkrb2, d6jkrb3
  • Chain 'C':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jkrc1, d6jkrc2
  • Chain 'D':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (2-327)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6jkrd1, d6jkrd2, d6jkrd3
  • Chain 'E':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (2-327)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6jkre1, d6jkre2, d6jkre3
  • Chain 'F':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jkrf1, d6jkrf2
  • Heterogens: CP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jkrA (A:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkrA (A:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpra
ayfrqmrygmfmrmailwsvla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jkrB (B:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkrB (B:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrma
ilwsvla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6jkrC (C:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkrC (C:)
elppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffeds
srtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqdaiee
alsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkl
lvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttr
lqaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailws
vla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6jkrD (D:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkrD (D:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqakaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmr
mailwsvla

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6jkrE (E:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkrE (E:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrm
ailwsvla

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6jkrF (F:)
gsmlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplf
fedssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqd
aieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhs
llkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvl
yttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttv
dadpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkrF (F:)
lelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffed
ssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqdaie
ealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllk
llvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlytt
rlqkerfstsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpr
aayfrqmrygmfmrmailwsvla