PDB entry 6jkq

View 6jkq on RCSB PDB site
Description: Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi (Ligand-free form)
Class: transferase
Keywords: ATCase, Pyrimidine metabolism, TRANSFERASE
Deposited on 2019-03-01, released 2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.08: d6jkqa1, d6jkqa2, d6jkqa3
  • Chain 'B':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jkqb1, d6jkqb2
  • Chain 'C':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.08: d6jkqc1, d6jkqc2, d6jkqc3
  • Chain 'D':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15636 (1-326)
      • expression tag (0)
    Domains in SCOPe 2.08: d6jkqd1, d6jkqd2, d6jkqd3
  • Chain 'E':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jkqe1, d6jkqe2
  • Chain 'F':
    Compound: aspartate carbamoyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: C3747_31g124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jkqf1, d6jkqf2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jkqA (A:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkqA (A:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkvgetladtirtldsysdvlvmrhprqdaieealsv
aqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrn
fsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlqak
aditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailwsvl
a

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jkqB (B:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkqB (B:)
elppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffeds
srtfssfcaamirlggsvvnfkvgetladtirtldsysdvlvmrhprqdaieealsvaqh
pilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrnfsi
kcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlqditid
aarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailwsvla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6jkqC (C:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkqC (C:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkvekgetladtirtldsysdvlvmrhprqdaieeal
svaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllv
rnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlq
daaalqsfaakaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygm
fmrmailwsvla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6jkqD (D:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkqD (D:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkvgetladtirtldsysdvlvmrhprqdaieealsv
aqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrn
fsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlqit
idaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailwsvla

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6jkqE (E:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkqE (E:)
elppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffeds
srtfssfcaamirlggsvvnfkvgetladtirtldsysdvlvmrhprqdaieealsvaqh
pilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrnfsi
kcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlditida
armrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailwsvla

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6jkqF (F:)
smlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplff
edssrtfssfcaamirlggsvvnfkveassinkgetladtirtldsysdvlvmrhprqda
ieealsvaqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsl
lkllvrnfsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvly
ttrlqkerfmastsddaaalqsfaakaditidaarmrlakekmivmhplprndelsttvd
adpraayfrqmrygmfmrmailwsvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6jkqF (F:)
mlelppvaslkgksitsaeqfsradiyalihlasamqrkidagevlnllqgrimtplffe
dssrtfssfcaamirlggsvvnfkvegetladtirtldsysdvlvmrhprqdaieealsv
aqhpilnagngagehptqalldtltihselgsvdgitialigdlkmgrtvhsllkllvrn
fsikcvflvapdalqmpqdvleplqheiatkgviihrthaltdevmqksdvlyttrlqsf
aakaditidaarmrlakekmivmhplprndelsttvdadpraayfrqmrygmfmrmailw
svla