PDB entry 6jio

View 6jio on RCSB PDB site
Description: Human LXR-beta in complex with a ligand
Class: DNA binding protein
Keywords: Nuclear receptor, DNA BINDING PROTEIN
Deposited on 2019-02-22, released 2019-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-16, with a file datestamp of 2019-10-11.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • engineered mutation (55)
      • engineered mutation (57)
      • expression tag (261-270)
    Domains in SCOPe 2.08: d6jioa1, d6jioa2
  • Chain 'B':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • expression tag (260-270)
    Domains in SCOPe 2.08: d6jiob1, d6jiob2
  • Chain 'C':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • engineered mutation (57)
      • expression tag (260-270)
    Domains in SCOPe 2.08: d6jioc1, d6jioc2
  • Chain 'D':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55055
      • engineered mutation (52)
      • engineered mutation (54-55)
      • engineered mutation (57)
      • expression tag (261-270)
    Domains in SCOPe 2.08: d6jiod1, d6jiod2
  • Heterogens: BQ3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jioA (A:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6jioA (A:)
vqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwpsasqqrfahftelaiisvqeivdf
akqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhragl
qvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyvealls
ytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdvhkilhr
llqd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jioB (B:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6jioB (B:)
vqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplqqrfahftelaiisvqeivdfak
qvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhraglqv
efinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsyt
rikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdshkilhrll
qd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6jioC (C:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6jioC (C:)
vqltaaqelmiqqlvaaqlqcnkrsfsdqpsqqrfahftelaiisvqeivdfakqvpgfl
qlgredqiallkastieimlletarrynhetecitflkdftyskddfhraglqvefinpi
fefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsytrikrpq
dqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdvshkilhrllqd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6jioD (D:)
mghhhhhhgegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqq
rfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetec
itflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnv
qepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqd
kklppllseiwdvhegsgsgshkilhrllqdsss

    Sequence, based on observed residues (ATOM records): (download) 
    >6jioD (D:)
taaqelmiqqlvaaqlqcnkrsfsdqpkvtpwpadpasgsasqqrfahftelaiisvqei
vdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhr
aglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyvea
llsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdvhki
lhrllqd