PDB entry 6jfv

View 6jfv on RCSB PDB site
Description: The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14)
Class: cytosolic protein
Keywords: Intermediate filaments, Keratinocytes, Skin, Epithelium, Protein Self-assembly, CYTOSOLIC PROTEIN
Deposited on 2019-02-12, released 2020-01-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-15, with a file datestamp of 2020-04-10.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Keratin, type I cytoskeletal 14
    Species: Homo sapiens [TaxId:9606]
    Gene: KRT14
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02533 (0-End)
      • engineered mutation (40)
    Domains in SCOPe 2.08: d6jfva_
  • Chain 'B':
    Compound: Keratin, type II cytoskeletal 5
    Species: Homo sapiens [TaxId:9606]
    Gene: KRT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jfvb_
  • Chain 'C':
    Compound: Keratin, type I cytoskeletal 14
    Species: Homo sapiens [TaxId:9606]
    Gene: KRT14
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02533 (Start-94)
      • engineered mutation (40)
    Domains in SCOPe 2.08: d6jfvc_
  • Chain 'D':
    Compound: Keratin, type II cytoskeletal 5
    Species: Homo sapiens [TaxId:9606]
    Gene: KRT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jfvd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jfvA (A:)
gkseiselrrtmqnleielqsqlsmkaslensleetkgryamqlaqiqemigsveeqlaq
lrcemeqqnqeykilldvktrleqeiatyrrlleg

    Sequence, based on observed residues (ATOM records): (download) 
    >6jfvA (A:)
gkseiselrrtmqnleielqsqlsmkaslensleetkgryamqlaqiqemigsveeqlaq
lrcemeqqnqeykilldvktrleqeiatyrrll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jfvB (B:)
lrntkheisemnrmiqrlraeidnvkkqcanlqnaiadaeqrgelalkdarnklaeleea
lqkakqdmarllreyqelmntklaldveiatyrklleg

    Sequence, based on observed residues (ATOM records): (download) 
    >6jfvB (B:)
tkheisemnrmiqrlraeidnvkkqcanlqnaiadaeqrgelalkdarnklaeleealqk
akqdmarllreyqelmntklaldveiatyrklleg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6jfvC (C:)
gkseiselrrtmqnleielqsqlsmkaslensleetkgryamqlaqiqemigsveeqlaq
lrcemeqqnqeykilldvktrleqeiatyrrlleg

    Sequence, based on observed residues (ATOM records): (download) 
    >6jfvC (C:)
seiselrrtmqnleielqsqlsmkaslensleetkgryamqlaqiqemigsveeqlaqlr
cemeqqnqeykilldvktrleqeiatyrrlleg

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6jfvD (D:)
lrntkheisemnrmiqrlraeidnvkkqcanlqnaiadaeqrgelalkdarnklaeleea
lqkakqdmarllreyqelmntklaldveiatyrklleg