PDB entry 6jcl

View 6jcl on RCSB PDB site
Description: crystal structure of cofactor-bound rv0187 from mtb
Deposited on 2019-01-29, released 2019-12-11
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
    • Uniprot O07431 (Start-219)
      • expression tag (220-221)
  • Chain 'B':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
    • Uniprot O07431 (Start-219)
      • expression tag (220-221)
  • Chain 'C':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
    • Uniprot O07431 (Start-219)
      • expression tag (220-221)
  • Chain 'F':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
    • Uniprot O07431 (Start-219)
      • expression tag (220-222)
  • Chain 'H':
    Compound: Probable O-methyltransferase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: Rv0187
    Database cross-references and differences (RAF-indexed):
    • Uniprot O07431 (Start-219)
      • expression tag (220)
  • Heterogens: SAH, SR, MPD, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6jclA (A:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclA (A:)
qqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrv
leigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldt
lptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadava
arrtlqmmgehpgldataiqtvgrkgwdgfalalvren

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6jclB (B:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclB (B:)
qpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrvl
eigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldtl
ptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadavaa
rrtlqmmgehpgldataiqtvgrkgwdgfalalvren

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6jclC (C:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclC (C:)
qqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrv
leigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldt
lptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadava
arrtlqmmgehpgldataiqtvgrkgwdgfalalvr

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6jclD (D:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclD (D:)
qpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrvl
eigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldtl
ptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadavaa
rrtlqmmgehpgldataiqtvgrkgwdgfalalvr

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6jclE (E:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclE (E:)
qpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrvl
eigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldtl
ptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadavaa
rrtlqmmgehpgldataiqtvgrkgwdgfalalvren

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6jclF (F:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclF (F:)
qqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrv
leigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldt
lptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadava
arrtlqmmgehpgldataiqtvgrkgwdgfalalvr

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6jclG (G:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclG (G:)
qqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrv
leigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldt
lptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadava
arrtlqmmgehpgldataiqtvgrkgwdgfalalvrenl

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6jclH (H:)
mgmdqqpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiq
arrvleigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgp
aldtlptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesdda
davaarrtlqmmgehpgldataiqtvgrkgwdgfalalvrenlyfqgghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >6jclH (H:)
qpnppdvdafldstlvgddpalaaalaasdaaelpriavsaqqgkflcllagaiqarrvl
eigtlggfstiwlargagpqgrvvtleyqpkhaevarvnlqragvadrvevvvgpaldtl
ptlaggpfdlvfidadkennvayiqwairlarrgavivvdnvirgggilaesddadavaa
rrtlqmmgehpgldataiqtvgrkgwdgfalalvre