PDB entry 6jc2

View 6jc2 on RCSB PDB site
Description: Crystal structure of the Fab fragment of ipilimumab
Class: immune system
Keywords: ipilimumab, CTLA-4, IMMUNE SYSTEM
Deposited on 2019-01-27, released 2019-09-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-11, with a file datestamp of 2019-09-06.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Ipilimumab Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6JC2 (0-End)
    Domains in SCOPe 2.08: d6jc2h_
  • Chain 'L':
    Compound: Ipilimumab Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6JC2 (0-End)
    Domains in SCOPe 2.08: d6jc2l1, d6jc2l2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6jc2H (H:)
qvqlvesgggvvqpgrslrlscaasgftfssytmhwvrqapgkglewvtfisydgnnkyy
adsvkgrftisrdnskntlylqmnslraedtaiyycartgwlgpfdywgqgtlvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6jc2H (H:)
qvqlvesgggvvqpgrslrlscaasgftfssytmhwvrqapgkglewvtfisydgnnkyy
adsvkgrftisrdnskntlylqmnslraedtaiyycartgwlgpfdywgqgtlvtvssas
tkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6jc2L (L:)
eivltqspgtlslspgeratlscrasqsvgssylawyqqkpgqaprlliygafsratgip
drfsgsgsgtdftltisrlepedfavyycqqygsspwtfgqgtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6jc2L (L:)
eivltqspgtlslspgeratlscrasqsvgssylawyqqkpgqaprlliygafsratgip
drfsgsgsgtdftltisrlepedfavyycqqygsspwtfgqgtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrge