PDB entry 6jbt

View 6jbt on RCSB PDB site
Description: Complex structure of toripalimab-Fab and PD-1
Class: immune system
Keywords: toripalimab-Fab, PD-1, glycosylation, complex structure, IMMUNE SYSTEM
Deposited on 2019-01-26, released 2019-06-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-02.
Experiment type: XRAY
Resolution: 2.47 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'F':
    Compound: Programmed cell death protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Pdcd1, Pd1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jbtf_
  • Chain 'H':
    Compound: heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6JBT (0-222)
    Domains in SCOPe 2.08: d6jbth_
  • Chain 'L':
    Compound: light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6JBT (0-End)
    Domains in SCOPe 2.08: d6jbtl1, d6jbtl2
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6jbtF (F:)
mpgwfldspdrpwnpptfspallvvtegdnatftcsfsntsesfvlnwyrmspsnqtdkl
aafpedrsqpgqdcrfrvtqlpngrdfhmsvvrarrndsgtylcgaislapkaqikeslr
aelrvterraevptahpspsprpagqfqtlvhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6jbtF (F:)
pwnpptfspallvvtegdnatftcsfsntsesfvlnwyrmspsnqtdklaafpedcrfrv
tqlpngrdfhmsvvrarrndsgtylcgaislapkaqikeslraelrvterr

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6jbtH (H:)
qgqlvqsgaevkkpgasvkvsckasgytftdyemhwvrqapihglewigviesetggtay
nqkfkgrvtitadkststaymelsslrsedtavyycaregittvattyywyfdvwgqgtt
vtvssastkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrv

    Sequence, based on observed residues (ATOM records): (download) 
    >6jbtH (H:)
qgqlvqsgaevkkpgasvkvsckasgytftdyemhwvrqapihglewigviesetggtay
nqkfkgrvtitadkststaymelsslrsedtavyycaregittvattyywyfdvwgqgtt
vtvssastkgpsvfplapcstaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtktytcnvdhkpsntkvdkrv

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6jbtL (L:)
dvvmtqsplslpvtlgqpasiscrssqsivhsngntylewylqkpgqspqlliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedvgvyycfqgshvpltfgqgtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6jbtL (L:)
dvvmtqsplslpvtlgqpasiscrssqsivhsngntylewylqkpgqspqlliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedvgvyycfqgshvpltfgqgtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrge