PDB entry 6jb6

View 6jb6 on RCSB PDB site
Description: Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
Class: ligase
Keywords: complex, LIGASE
Deposited on 2019-01-25, released 2019-03-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-20, with a file datestamp of 2019-03-15.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-conjugating enzyme E2 K
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2K, HIP2, LIG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61086 (5-204)
      • expression tag (4)
      • engineered mutation (96)
      • engineered mutation (101)
    Domains in SCOPe 2.08: d6jb6a1, d6jb6a2, d6jb6a3
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jb6b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6jb6A (A:)
    gamgsmaniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggr
    yqleikipetypfnppkvrfitkiwhpnissvtgaikldiladqwaaamtlrtvllslqa
    llaaaepddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfd
    rnavivalsskswdvetatelllsn
    

    Sequence, based on observed residues (ATOM records): (download)
    >6jb6A (A:)
    smaniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryqle
    ikipetypfnppkvrfitkiwhpnissvtgaikldiladqwaaamtlrtvllslqallaa
    aepddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrnav
    ivalsskswdvetatelllsn
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6jb6B (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg