PDB entry 6jae

View 6jae on RCSB PDB site
Description: Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with Pi (pyrophosphatase reaction)
Class: transferase
Keywords: trypanosoma, glycerol kinase, sugar kinase superfamily, transferase, glycosome
Deposited on 2019-01-24, released 2020-01-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-29, with a file datestamp of 2020-01-24.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.08: d6jaea1, d6jaea2, d6jaea3
  • Chain 'B':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.08: d6jaeb1, d6jaeb2, d6jaeb3
  • Chain 'C':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.08: d6jaec1, d6jaec2, d6jaec3
  • Chain 'D':
    Compound: glycerol kinase
    Species: Trypanosoma brucei gambiense [TaxId:31285]
    Gene: gk
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3KVM3 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.08: d6jaed1, d6jaed2, d6jaed3
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jaeA (A:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >6jaeA (A:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6jaeB (B:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >6jaeB (B:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6jaeC (C:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >6jaeC (C:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6jaeD (D:)
gidpftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsa
ckcmsvaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditk
kvtaelgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlm
yklsggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetd
ecgvaaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhg
llstvgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgiv
fvpafsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnl
sslrvdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkav
srrenswktvspsgsamereamiaewrealkrtkwakl

    Sequence, based on observed residues (ATOM records): (download) 
    >6jaeD (D:)
ftmkyvgsidqgttstrfiifderqrpvsvhqvphtqhtphpgwlehdpmeifrsackcm
svaiaklrqkdasfrkieaigitnqrettvawdrvtkeplcyapvwndlrtyditkkvta
elgggdsmfaskitglpvstyfaafkmrwmlenvpavadacrrgtlcfgtidtwlmykls
ggkafvtdvtnasrtflmdlrtrkwspelceklkipmetlpeirsnselfgyvetdecgv
aaalnertpimgsigdqqsalfgnmcfekgeakntygtgcfllmnvgeearfskhgllst
vgfqvgrdgpcyyalegaiacagatvewmrrnmnlfshiteceklarsvpgtqgivfvpa
fsgllapywdpsargtivgmtlkttrahviraalqaialqlndvvgsmkrdaglnlsslr
vdgglskngllmeiqasllgvdilvpsmhettalgaalcaglaagvwtsleevkavsrre
nswktvspsgsamereamiaewrealkrtkwak